247942

Gene Symbol:

CFLAR HGSNAT LOC400002 METTL21A NEK5

Gene Name:

CASP8 and FADD like apoptosis regulator

heparan-alpha-glucosaminide N-acetyltransferase

uncharacterized LOC400002

methyltransferase like 21A

NIMA related kinase 5

Gene Aliases:

CASH, CASP8AP1, CLARP, Casper, FLAME, FLAME-1, FLAME1, FLIP, I-FLICE, MRIT, c-FLIP, c-FLIPL, c-FLIPR, c-FLIPS

HGNAT, MPS3C, RP73, TMEM76

-

FAM119A, HCA557b, HSPA-KMT

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Chromosome Location:

Chr.2: 201116015 - 201172688 on Build GRCh38

Chromosome Location:

Chr.8: 43140449 - 43202827 on Build GRCh38

Chromosome Location:

Chr.12: 9948137 - 9953337 on Build GRCh38

Chromosome Location:

Chr.2: 207580631 - 207625928 on Build GRCh38

Chromosome Location:

Chr.13: 52064762 - 52129092 on Build GRCh38

UniGene ID:

Hs.390736

Hs.600384

-

Hs.664764

Hs.672144

Species:

Human

Species Specific ID (Flybase ID):

-

-

-

-

-

siRNA Details

Gene Symbol: CFLAR
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	NM_001127183.2	NP_001120655.1	10	4491
	NM_001202515.1	NP_001189444.1	6	3557
	NM_001202516.1	NP_001189445.1	8	4358
	NM_001202517.1	NP_001189446.1	9	4045
	NM_001202518.1	NP_001189447.1	8	4620
	NM_001202519.1	NP_001189448.1	9	4884
	NM_003879.5	NP_003870.4	10	4463
	XM_017005189.1	XP_016860678.1	11	5358
	XM_017005190.1	XP_016860679.1	10	4327
	XM_017005191.1	XP_016860680.1	10	4406
	XM_017005192.1	XP_016860681.1	10	5293
	XM_017005193.1	XP_016860682.1	10	7310
	XM_017005194.1	XP_016860683.1	10	5166
	XM_017005195.1	XP_016860684.1	11	4504
	XM_017005196.1	XP_016860685.1	8	4129

Gene Symbol: HGSNAT
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
GenBank mRNA	AK057293.1	-	1	216

Gene Symbol: LOC400002
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	NR_135047.1		1	554
GenBank mRNA	AK128230.1	-	1	555

Gene Symbol: METTL21A
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	NM_001127395.2	NP_001120867.1	4	3598
	NM_145280.5	NP_660323.3	4	3459

Gene Symbol: NEK5
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
GenBank mRNA	AK126330.1	-	9	3248

More Information

Additional Information:

This siRNA no longer meets our design criteria. We suggest you choose a different siRNA for this gene or contact Tech Support for more information.

Gene Ontology Categories:

Process(es)

proteolysis
apoptotic process
skeletal muscle tissue development
skeletal muscle atrophy
regulation of skeletal muscle satellite cell proliferation
skeletal myofibril assembly
viral process
negative regulation of apoptotic process
positive regulation of catalytic activity
positive regulation of I-kappaB kinase/NF-kappaB signaling
skeletal muscle tissue regeneration
positive regulation of NF-kappaB transcription factor activity
regulation of necroptotic process
execution phase of apoptosis
negative regulation of myoblast fusion
regulation of extrinsic apoptotic signaling pathway via death domain receptors
negative regulation of extrinsic apoptotic signaling pathway via death domain receptors
negative regulation of extrinsic apoptotic signaling pathway
protein methylation
peptidyl-lysine methylation
regulation of ATPase activity

Function(s)

protease binding
death receptor binding
protein binding
enzyme activator activity
protein complex binding
cysteine-type endopeptidase activity involved in execution phase of apoptosis
protein-lysine N-methyltransferase activity
Hsp70 protein binding
ATPase binding