249711

Gene Symbol:

MTHFD1L LOC100133920 LOC100996643 LOC101928195 LOC101929583 LOC102724580 LOC102724904 LOC105379443 LOC286297

Gene Name:

methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1-like

methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1-like pseudogene

monofunctional C1-tetrahydrofolate synthase, mitochondrial-like

methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1-like pseudogene

methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1-like pseudogene

methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1-like pseudogene

monofunctional C1-tetrahydrofolate synthase, mitochondrial-like

monofunctional C1-tetrahydrofolate synthase, mitochondrial-like

methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1-like pseudogene

Gene Aliases:

FTHFSDC1, MTC1THFS, dJ292B18.2

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Chromosome Location:

Chr.6: 150865679 - 151101887 on Build GRCh38

Chromosome Location:

Chr.2: 94575976 - 94587183 on Build GRCh38

Chromosome Location:

Chr.9: 63333302 - 63434724 on Build GRCh38

Chromosome Location:

Chr.9: 65836970 - 65877274 on Build GRCh38

Chromosome Location:

Chr.9: 64639734 - 64700461 on Build GRCh38

Chromosome Location:

Chr.9: 40499981 - 40578494 on Build GRCh38

Chromosome Location:

Chr.9: 43126375 - 43153730 on Build GRCh38

Chromosome Location:

Chr.9: 65142831 - 65204239 on Build GRCh38

Chromosome Location:

Chr.9: 63112403 - 63127100 on Build GRCh38

UniGene ID:

Hs.591343

Hs.645503

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Hs.404758

Hs.404758

Hs.494013

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Hs.645503

Species:

Human

Species Specific ID (Flybase ID):

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siRNA Details

Gene Symbol: MTHFD1L
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	NM_001242767.1	NP_001229696.1	26	2983
	NM_001242768.1	NP_001229697.1	26	2667
	NM_015440.4	NP_056255.2	26	2980
	XM_005266907.4	XP_005266964.1	26	2921
	XM_005266910.4	XP_005266967.1	26	2924
	XM_011535729.2	XP_011534031.1	26	2924
	XM_011535730.2	XP_011534032.1	26	2667
	XM_011535731.2	XP_011534033.1	26	2639
	XM_011535732.2	XP_011534034.1	26	2721
	XM_011535733.2	XP_011534035.1	26	3167
	XM_011535734.2	XP_011534036.1	26	2760
	XM_017010702.1	XP_016866191.1	26	2923
	XM_017010703.1	XP_016866192.1	26	2923
	XM_017010704.1	XP_016866193.1	26	2639
	XM_017010705.1	XP_016866194.1	26	3164
	XM_017010706.1	XP_016866195.1	26	3167
	XM_017010707.1	XP_016866196.1	26	3164
GenBank mRNA	AB127387.1	-	26	2836
	AK024798.1	-	10	1068
	AK127089.1	-	25	3459
	AK315378.1	-	25	2776
	AL117452.1	-	26	2655
	AY374130.1	-	26	2943
	BC008629.1	-	12	1249
	BC017477.1	-	21	2227
	BC110319.1	-	25	2602
	BC136685.1	-	26	2873	9020675
	BC144368.1	-	26	2873	9052889
	BC144369.1	-	26	2870

Gene Symbol: LOC100133920
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	NR_024443.3		3	353
GenBank mRNA	AK074198.1	-	3	353

Gene Symbol: LOC100996643
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	XM_003846387.5	XP_003846435.2	4	431
	XM_005272561.4	XP_005272618.1	4	431
	XM_006716909.3	XP_006716972.1	4	431
	XM_006716910.3	XP_006716973.1	3	392
	XM_006716911.3	XP_006716974.1	4	431
	XM_006716912.3	XP_006716975.1	4	438
	XM_011545675.2	XP_011543977.1	4	468

Gene Symbol: LOC101928195
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	NR_135597.1		4	509

Gene Symbol: LOC101929583
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	NR_136299.1		3	301

Gene Symbol: LOC102724580
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	NR_136300.1		3	577

Gene Symbol: LOC102724904
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	XM_011518105.2	XP_011516407.1	3	404

Gene Symbol: LOC105379443
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	XM_011545676.2	XP_011543978.1	3	494
	XM_011545677.2	XP_011543979.1	3	494
	XM_011545678.2	XP_011543980.1	3	494
	XM_017015396.1	XP_016870885.1	3	455

Gene Symbol: LOC286297
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	NR_046175.1		3	890
GenBank mRNA	AK097152.1	-	3	892

More Information

Additional Information:

This siRNA no longer meets our design criteria. We suggest you choose a different siRNA for this gene or contact Tech Support for more information.

Gene Ontology Categories:

Process(es)

neural tube closure
one-carbon metabolic process
folic acid-containing compound metabolic process
folic acid-containing compound biosynthetic process
formate metabolic process
tetrahydrofolate interconversion
tetrahydrofolate metabolic process
folic acid metabolic process
embryonic neurocranium morphogenesis
embryonic viscerocranium morphogenesis
oxidation-reduction process

Function(s)

formate-tetrahydrofolate ligase activity
methenyltetrahydrofolate cyclohydrolase activity
methylenetetrahydrofolate dehydrogenase (NADP+) activity
ATP binding
protein homodimerization activity