24979

• Gene Symbol: TERF1
• Gene Name: telomeric repeat binding factor 1
• Gene Aliases: PIN2, TRBF1, TRF, TRF1, hTRF1-AS, t-TRF1
• Chromosome Location: Chr.8: 73008862 - 73047752 on Build GRCh38
• UniGene ID: Hs.442707
• Species: Human
• Species Specific ID (Flybase ID): -

siRNA Details

Gene Symbol: TERF1
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	NM_003218.3	NP_003209.2	1, 2	351
	NM_017489.2	NP_059523.2	1, 2	351
	XM_005251291.3	XP_005251348.1	1, 2	349
	XM_005251292.3	XP_005251349.1	1, 2	349
GenBank mRNA	AF003001.1	-	1, 2	341
	BC029378.1	-	1, 2	334	4724068
	BC071975.1	-	1, 2	327
	U40705.1	-	1, 2	341
	U74382.1	-	1, 2	326

More Information

Other Species Targeted

This siRNA also targets the following transcripts in Rat: NM_001012464, XM_006237729, BC089888.
This siRNA also targets the following transcripts in Mouse: NM_001286628, NM_009352, AK132022, BB652245, BC034866, and others.

Gene Ontology Categories:

Process(es)

telomere maintenance
telomere maintenance via telomerase
mitotic nuclear division
negative regulation of DNA replication
telomere capping
telomeric loop formation
negative regulation of telomere maintenance via telomerase
negative regulation of telomere maintenance via semi-conservative replication
response to drug
meiotic telomere clustering
cell division
negative regulation of telomerase activity
positive regulation of telosome assembly
negative regulation of establishment of protein localization to telomere
negative regulation of establishment of RNA localization to telomere
negative regulation of establishment of macromolecular complex localization to telomere

Function(s)

DNA binding
double-stranded telomeric DNA binding
telomerase activity
protein binding
DNA binding, bending
telomeric DNA binding
protein homodimerization activity
ubiquitin binding
G-rich strand telomeric DNA binding