249855

Gene Symbol:

CCL3 CCL3L1 CCL3L3

Gene Name:

C-C motif chemokine ligand 3

C-C motif chemokine ligand 3 like 1

C-C motif chemokine ligand 3 like 3

Gene Aliases:

G0S19-1, LD78ALPHA, MIP-1-alpha, MIP1A, SCYA3

464.2, D17S1718, G0S19-2, LD78, LD78-beta(1-70), LD78BETA, MIP1AP, SCYA3L, SCYA3L1

464.2, D17S1718, G0S19-2, LD78, LD78BETA, SCYA3L, SCYA3L1

Chromosome Location:

Chr.17: 36088256 - 36090160 on Build GRCh38

Chromosome Location:

-

Chromosome Location:

Chr.17: 36194869 - 36196748 on Build GRCh38

UniGene ID:

Hs.514107

Hs.512683

Hs.454713

Species:

Human

Species Specific ID (Flybase ID):

-

-

-

siRNA Details

Gene Symbol: CCL3
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	NM_002983.2	NP_002974.1	2	266
GenBank mRNA	AF043339.1	-	1	98
	BC071834.1	-	2	238	5935287
	BC171831.1	-	2	200	9054485
	BC171891.1	-	2	200	9054545
	BX103455.1	-	2	266
	D00044.1	-	2	247
	D63785.1	-	2	147
	M23452.1	-	2	247
	M25315.1	-	2	247
	X03754.1	-	2	247

Gene Symbol: CCL3L1
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	NM_021006.5	NP_066286.1	2	252
	NR_111964.1		2	444
GenBank mRNA	AV739733.1	-	2	296
	BC027888.1	-	2	240	5222247
	BC107710.1	-	2	256	6699133
	BC146914.1	-	2	203	9056842
	X52149.1	-	2	430

Gene Symbol: CCL3L3
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	NM_001001437.3	NP_001001437.2	2	242
GenBank mRNA	AI302038.1	-	2	143
	BC007783.2	-	2	237	4308472
	BC146919.1	-	2	203	9056847
	BC147008.1	-	2	203	9056936
	BC147013.1	-	2	203	9056941
	BT006783.1	-	2	167
	CF128666.1	-	2	221

More Information

Additional Information:

This siRNA no longer meets our design criteria. We suggest you choose a different siRNA for this gene or contact Tech Support for more information.

Gene Ontology Categories:

Process(es)

MAPK cascade
osteoblast differentiation
cell activation
monocyte chemotaxis
calcium ion transport
cellular calcium ion homeostasis
exocytosis
chemotaxis
inflammatory response
cytoskeleton organization
G-protein coupled receptor signaling pathway
cell-cell signaling
behavior
regulation of cell shape
response to toxic substance
positive regulation of gene expression
negative regulation of gene expression
T cell chemotaxis
release of sequestered calcium ion into cytosol by sarcoplasmic reticulum
calcium-mediated signaling
signaling
positive regulation of cell migration
negative regulation of bone mineralization
neutrophil chemotaxis
lipopolysaccharide-mediated signaling pathway
positive regulation of tumor necrosis factor production
eosinophil degranulation
protein kinase B signaling
positive regulation of neuron apoptotic process
positive regulation of GTPase activity
astrocyte cell migration
negative regulation by host of viral transcription
negative regulation of osteoclast differentiation
eosinophil chemotaxis
macrophage chemotaxis
lymphocyte chemotaxis
positive regulation of interleukin-1 beta secretion
positive regulation of inflammatory response
positive regulation of calcium-mediated signaling
positive chemotaxis
positive regulation of protein kinase B signaling
positive regulation of calcium ion transport
regulation of sensory perception of pain
chemokine-mediated signaling pathway
positive regulation of ERK1 and ERK2 cascade
response to cholesterol
cellular response to interferon-gamma
cellular response to interleukin-1
cellular response to tumor necrosis factor
cellular response to organic cyclic compound
granulocyte chemotaxis
positive regulation of calcium ion import
positive regulation of natural killer cell chemotaxis
negative regulation of cell proliferation

Function(s)

protein kinase activity
calcium-dependent protein kinase C activity
protein binding
chemokine activity
phospholipase activator activity
kinase activity
CCR1 chemokine receptor binding
CCR5 chemokine receptor binding
chemoattractant activity
identical protein binding
CCR chemokine receptor binding