250223

Gene Symbol:

MIPOL1 CFLAR KCNQ1OT1 LINC00504 LOC100131257 SMC5-AS1 TBC1D8B UGDH-AS1

Gene Name:

mirror-image polydactyly 1

CASP8 and FADD like apoptosis regulator

KCNQ1 opposite strand/antisense transcript 1 (non-protein coding)

long intergenic non-protein coding RNA 504

zinc finger protein 655 pseudogene

SMC5 antisense RNA 1 (head to head)

TBC1 domain family member 8B

UGDH antisense RNA 1

Gene Aliases:

CCDC193

CASH, CASP8AP1, CLARP, Casper, FLAME, FLAME-1, FLAME1, FLIP, I-FLICE, MRIT, c-FLIP, c-FLIPL, c-FLIPR, c-FLIPS

KCNQ1-AS2, KCNQ10T1, Kncq1, KvDMR1, KvLQT1-AS, LIT1, NCRNA00012

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MAMDC2-AS2

GRAMD8B

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Chromosome Location:

Chr.14: 37197888 - 37579207 on Build GRCh38

Chromosome Location:

Chr.2: 201116015 - 201172688 on Build GRCh38

Chromosome Location:

Chr.11: 2608328 - 2699998 on Build GRCh38

Chromosome Location:

Chr.4: 14470465 - 14888169 on Build GRCh38

Chromosome Location:

Chr.7: 7075770 - 7096786 on Build GRCh38

Chromosome Location:

Chr.9: 70216059 - 70258874 on Build GRCh38

Chromosome Location:

Chr.X: 106802689 - 106876150 on Build GRCh38

Chromosome Location:

Chr.4: 39527839 - 39594707 on Build GRCh38

UniGene ID:

Hs.660396

Hs.390736

Hs.604823

Hs.551051

Hs.551110

Hs.556816

Hs.351798

Hs.640769

Species:

Human

Species Specific ID (Flybase ID):

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siRNA Details

Gene Symbol: MIPOL1
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
GenBank mRNA	BX647795.1	-	10	5152

Gene Symbol: CFLAR
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	NM_001127183.2	NP_001120655.1	10	6341
	NM_001202515.1	NP_001189444.1	6	5407
	NM_001202516.1	NP_001189445.1	8	6208
	NM_001202517.1	NP_001189446.1	9	5895
	NM_001202518.1	NP_001189447.1	8	6470
	NM_001202519.1	NP_001189448.1	9	6734
	NM_003879.5	NP_003870.4	10	6313
	XM_017005189.1	XP_016860678.1	11	7208
	XM_017005190.1	XP_016860679.1	10	6177
	XM_017005191.1	XP_016860680.1	10	6256
	XM_017005192.1	XP_016860681.1	10	7143
	XM_017005193.1	XP_016860682.1	10	9160
	XM_017005194.1	XP_016860683.1	10	7016
	XM_017005195.1	XP_016860684.1	11	6354
	XM_017005196.1	XP_016860685.1	8	5979

Gene Symbol: KCNQ1OT1
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	NR_002728.3		1	63554

Gene Symbol: LINC00504
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	NR_126435.1		7	1688
GenBank mRNA	BC036758.2	-	7	1700	5563071

Gene Symbol: LOC100131257
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	NR_034022.1		1	11094

Gene Symbol: SMC5-AS1
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
GenBank mRNA	CR936772.1	-	3	5350

Gene Symbol: TBC1D8B
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
GenBank mRNA	BX648230.1	-	7	2709

Gene Symbol: UGDH-AS1
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	NR_047679.1		5	1566
GenBank mRNA	AK056558.1	-	5	1386

More Information

Additional Information:

This siRNA no longer meets our design criteria. We suggest you choose a different siRNA for this gene or contact Tech Support for more information.

Gene Ontology Categories:

Process(es)

proteolysis
apoptotic process
skeletal muscle tissue development
skeletal muscle atrophy
regulation of skeletal muscle satellite cell proliferation
skeletal myofibril assembly
viral process
negative regulation of apoptotic process
positive regulation of catalytic activity
positive regulation of I-kappaB kinase/NF-kappaB signaling
skeletal muscle tissue regeneration
positive regulation of NF-kappaB transcription factor activity
regulation of necroptotic process
execution phase of apoptosis
negative regulation of myoblast fusion
regulation of extrinsic apoptotic signaling pathway via death domain receptors
negative regulation of extrinsic apoptotic signaling pathway via death domain receptors
negative regulation of extrinsic apoptotic signaling pathway

Function(s)

protease binding
death receptor binding
protein binding
enzyme activator activity
protein complex binding
cysteine-type endopeptidase activity involved in execution phase of apoptosis