250518

Gene Symbol:

ARHGEF5 ARHGEF34P

Gene Name:

Rho guanine nucleotide exchange factor 5

Rho guanine nucleotide exchange factor 34, pseudogene

Gene Aliases:

GEF5, P60, TIM, TIM1

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Chromosome Location:

Chr.7: 144355341 - 144380632 on Build GRCh38

Chromosome Location:

Chr.7: 144258996 - 144286003 on Build GRCh38

UniGene ID:

Hs.334

Hs.744262

Species:

Human

Species Specific ID (Flybase ID):

-

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siRNA Details

Gene Symbol: ARHGEF5
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	NM_005435.3	NP_005426.2	2	2260
	XM_017012623.1	XP_016868112.1	2	2315
GenBank mRNA	AK123596.1	-	1	459
	AK160365.1	-	2	2316
	BC136661.1	-	2	2174	9020651
	BX649178.1	-	1	145
	CR749203.1	-	2	2200

Gene Symbol: ARHGEF34P
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	NR_033942.1		1	1179

More Information

Additional Information:

This siRNA no longer meets our design criteria. We suggest you choose a different siRNA for this gene or contact Tech Support for more information.

Gene Ontology Categories:

Process(es)

myeloid dendritic cell chemotaxis
actin cytoskeleton organization
regulation of actin cytoskeleton organization
regulation of Rho protein signal transduction
intracellular signal transduction
regulation of GTPase activity
positive regulation of JUN kinase activity
positive regulation of GTPase activity
positive regulation of sequence-specific DNA binding transcription factor activity
regulation of cytoskeleton organization
positive regulation of stress fiber assembly
regulation of ERK1 and ERK2 cascade
positive regulation of podosome assembly
positive regulation of protein import

Function(s)

guanyl-nucleotide exchange factor activity
Rho guanyl-nucleotide exchange factor activity
protein binding
GTP binding
lipid binding