250679

Gene Symbol:

PMS2 DTX2P1-UPK3BP1-PMS2P11 LOC441259 PMS2P1 PMS2P10 PMS2P2 PMS2P3 PMS2P4 PMS2P5 PMS2P6 PMS2P7 PMS2P9

Gene Name:

PMS1 homolog 2, mismatch repair system component

DTX2P1-UPK3BP1-PMS2P11 readthrough, transcribed pseudogene

PMS1 homolog 2, mismatch repair system component pseudogene

PMS1 homolog 2, mismatch repair system component pseudogene 1

PMS1 homolog 2, mismatch repair system component pseudogene 10

PMS1 homolog 2, mismatch repair system component pseudogene 2

PMS1 homolog 2, mismatch repair system component pseudogene 3

PMS1 homolog 2, mismatch repair system component pseudogene 4

PMS1 homolog 2, mismatch repair system component pseudogene 5

PMS1 homolog 2, mismatch repair system component pseudogene 6

PMS1 homolog 2, mismatch repair system component pseudogene 7

PMS1 homolog 2, mismatch repair system component pseudogene 9

Gene Aliases:

HNPCC4, MLH4, PMS2CL, PMSL2

PMS2L11

-

PMS2L1, PMS2L13, PMS2L6, PMS2L7, PMS2L8, PMS3, PMS8, PMSR1, PMSR2

PMS2L10, PMSR4

PMS2L2, PMS4

PMS2L3, PMS2L9, PMS5, PMSR3

PMS2L4, PMS6

PMS2L5, PMS7

PMS2L14

PMS2L15, PMS2LP2, PMSR7

PMS2L17, PMS2LP1, PMSR5

Chromosome Location:

Chr.7: 5970925 - 6009106 on Build GRCh38

Chromosome Location:

Chr.7: 76980822 - 77023761 on Build GRCh38

Chromosome Location:

Chr.7: 75296553 - 75299806 on Build GRCh38

Chromosome Location:

Chr.7: 100320640 - 100336307 on Build GRCh38

Chromosome Location:

Chr.7: 75324481 - 75327776 on Build GRCh38

Chromosome Location:

Chr.7: 75343937 - 75358997 on Build GRCh38

Chromosome Location:

Chr.7: 75507747 - 75528123 on Build GRCh38

Chromosome Location:

Chr.7: 67276131 - 67302442 on Build GRCh38

Chromosome Location:

Chr.7: 74890768 - 74921138 on Build GRCh38

Chromosome Location:

Chr.7: 73093644 - 73096950 on Build GRCh38

Chromosome Location:

Chr.7: 73006080 - 73016375 on Build GRCh38

Chromosome Location:

Chr.7: 77039480 - 77053038 on Build GRCh38

UniGene ID:

Hs.632637

Hs.675888

Hs.292996

Hs.634244

-

Hs.292996

Hs.659871

Hs.712714

Hs.292996

Hs.661055

Hs.292996

Hs.292996

Species:

Human

Species Specific ID (Flybase ID):

-

-

-

-

-

-

-

-

-

-

-

-

siRNA Details

Gene Symbol: PMS2
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	NM_000535.6	NP_000526.2	3	312
	NM_001322003.1	NP_001308932.1	3	307
	NM_001322004.1	NP_001308933.1	2	172
	NM_001322005.1	NP_001308934.1	3	424
	NM_001322006.1	NP_001308935.1	3	312
	NM_001322007.1	NP_001308936.1	3	312
	NM_001322008.1	NP_001308937.1	2	172
	NM_001322009.1	NP_001308938.1	3	419
	NM_001322010.1	NP_001308939.1	2	172
	NM_001322011.1	NP_001308940.1	3	312
	NM_001322012.1	NP_001308941.1	3	307
	NM_001322013.1	NP_001308942.1	3	307
	NM_001322014.1	NP_001308943.1	3	312
	NM_001322015.1	NP_001308944.1	3	307
	NR_136154.1		3	312
	XM_017012342.1	XP_016867831.1	3	286
GenBank mRNA	AB103082.1	-	3	225
	AB103083.1	-	3	225
	AB103085.1	-	2	225
	AK294661.1	-	2	162
	AK312390.1	-	3	261
	BC008400.1	-	3	270
	BC031832.1	-	3	276
	BC093921.1	-	3	247	7939766
	BX537558.1	-	3	426
	CR981250.1	-	3	213
	DA774159.1	-	3	312
	U14658.1	-	3	227

Gene Symbol: DTX2P1-UPK3BP1-PMS2P11
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	NR_023383.1		8	1297
GenBank mRNA	U38980.1	-	8	1183

Gene Symbol: LOC441259
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
GenBank mRNA	BC075816.1	-	3	236

Gene Symbol: PMS2P1
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	NR_003613.1		3	672
GenBank mRNA	AB017004.1	-	3	672
	BC067809.1	-	3	304
	BC110395.1	-	3	280
	D38435.1	-	3	275
	D38499.1	-	3	275

Gene Symbol: PMS2P10
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
GenBank mRNA	BC047753.1	-	3	232

Gene Symbol: PMS2P2
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	NR_003614.3		3	256
GenBank mRNA	DA215155.1	-	3	243

Gene Symbol: PMS2P3
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	NR_028059.1		6	1058
GenBank mRNA	BC101598.1	-	5	509	8069104
	D38437.1	-	2	207
	D38498.1	-	2	207

Gene Symbol: PMS2P4
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	NR_022007.2		3	269
	NR_046297.1		3	269
	NR_046299.1		3	269
GenBank mRNA	BC029368.1	-	3	246
	BC029419.1	-	3	234
	CB141754.1	-	3	234
	D38438.1	-	3	240
	D38500.1	-	3	240
	DA885243.1	-	3	270

Gene Symbol: PMS2P5
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	NR_027775.2		3	281
	NR_027776.2		3	281
GenBank mRNA	AK309660.1	-	3	229
	BF984173.1	-	3	280
	D38436.1	-	3	262
	D38439.1	-	2	193
	D38501.1	-	2	193
	D38502.1	-	3	262
	DW407867.1	-	3	298

Gene Symbol: PMS2P6
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
GenBank mRNA	AB017005.1	-	4	434

Gene Symbol: PMS2P7
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	NR_130940.1		3	297
GenBank mRNA	AB017006.1	-	3	392
	DB472687.1	-	3	297

Gene Symbol: PMS2P9
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	NR_028058.1		2	672
GenBank mRNA	BM845848.1	-	2	100

More Information

Additional Information:

This siRNA no longer meets our design criteria. We suggest you choose a different siRNA for this gene or contact Tech Support for more information.

Gene Ontology Categories:

Process(es)

mismatch repair
somatic hypermutation of immunoglobulin genes
response to drug
nucleic acid phosphodiester bond hydrolysis
phosphorylation
regulation of transcription, DNA-templated
biological_process

Function(s)

DNA binding
single-stranded DNA binding
endonuclease activity
protein binding
ATP binding
ATPase activity
single base insertion or deletion binding
MutSalpha complex binding
kinase activity
molecular_function