251143

Gene Symbol:

CFLAR ACOT11 ERVK-1 FKSG49 HELLPAR ORC6 RRM1-AS1 SEC11A SPICE1

Gene Name:

CASP8 and FADD like apoptosis regulator

acyl-CoA thioesterase 11

endogenous retrovirus group K member 1

FKSG49

HELLP associated long non-coding RNA

origin recognition complex subunit 6

RRM1 antisense RNA 1

SEC11 homolog A, signal peptidase complex subunit

spindle and centriole associated protein 1

Gene Aliases:

CASH, CASP8AP1, CLARP, Casper, FLAME, FLAME-1, FLAME1, FLIP, I-FLICE, MRIT, c-FLIP, c-FLIPL, c-FLIPR, c-FLIPS

BFIT, STARD14, THEA, THEM1

c1_A

FKSG52, FKSG55, FKSG56, FKSG57, FKSG60, FKSG61, FKSG64, FKSG65, FKSG66, FKSG67, FKSG68, FKSG70

LINC-HELLP, lncHELLP

ORC6L

-

1810012E07Rik, SEC11L1, SPC18, SPCS4A, sid2895

CCDC52, SPICE

Chromosome Location:

Chr.2: 201116015 - 201172688 on Build GRCh38

Chromosome Location:

Chr.1: 54548134 - 54634744 on Build GRCh38

Chromosome Location:

-

Chromosome Location:

-

Chromosome Location:

-

Chromosome Location:

Chr.16: 46689646 - 46698394 on Build GRCh38

Chromosome Location:

-

Chromosome Location:

Chr.15: 84669537 - 84716460 on Build GRCh38

Chromosome Location:

Chr.3: 113442718 - 113515187 on Build GRCh38

UniGene ID:

Hs.390736

Hs.745173

-

-

Hs.160562

Hs.49760

Hs.445705

Hs.9534

Hs.477144

Species:

Human

Species Specific ID (Flybase ID):

-

-

-

-

-

-

-

-

-

siRNA Details

Gene Symbol: CFLAR
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	NM_001127183.2	NP_001120655.1	10	3947
	NM_001202515.1	NP_001189444.1	6	3013
	NM_001202516.1	NP_001189445.1	8	3814
	NM_001202517.1	NP_001189446.1	9	3501
	NM_001202518.1	NP_001189447.1	8	4076
	NM_001202519.1	NP_001189448.1	9	4340
	NM_003879.5	NP_003870.4	10	3919
	XM_017005189.1	XP_016860678.1	11	4814
	XM_017005190.1	XP_016860679.1	10	3783
	XM_017005191.1	XP_016860680.1	10	3862
	XM_017005192.1	XP_016860681.1	10	4749
	XM_017005193.1	XP_016860682.1	10	6766
	XM_017005194.1	XP_016860683.1	10	4622
	XM_017005195.1	XP_016860684.1	11	3960
	XM_017005196.1	XP_016860685.1	8	3585

Gene Symbol: ACOT11
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
GenBank mRNA	AB014607.1	-	17	4223

Gene Symbol: ERVK-1
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
GenBank mRNA	BQ304053.1	-	1	111

Gene Symbol: FKSG49
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
GenBank mRNA	AF336887.1	-	1	303
	AF338196.1	-	1	321
	AF338199.1	-	1	276

Gene Symbol: HELLPAR
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
GenBank mRNA	JX088243.1	-	1	53455

Gene Symbol: ORC6
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
GenBank mRNA	AK024077.1	-	4	1581

Gene Symbol: RRM1-AS1
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
GenBank mRNA	H70418.1	-	1	59

Gene Symbol: SEC11A
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
GenBank mRNA	AB209437.1	-	1	462

Gene Symbol: SPICE1
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
GenBank mRNA	AL832327.2	-	12	3094

More Information

Additional Information:

This siRNA no longer meets our design criteria. We suggest you choose a different siRNA for this gene or contact Tech Support for more information.

Gene Ontology Categories:

Process(es)

proteolysis
apoptotic process
skeletal muscle tissue development
skeletal muscle atrophy
regulation of skeletal muscle satellite cell proliferation
skeletal myofibril assembly
viral process
negative regulation of apoptotic process
positive regulation of catalytic activity
positive regulation of I-kappaB kinase/NF-kappaB signaling
skeletal muscle tissue regeneration
positive regulation of NF-kappaB transcription factor activity
regulation of necroptotic process
execution phase of apoptosis
negative regulation of myoblast fusion
regulation of extrinsic apoptotic signaling pathway via death domain receptors
negative regulation of extrinsic apoptotic signaling pathway via death domain receptors
negative regulation of extrinsic apoptotic signaling pathway

Function(s)

protease binding
death receptor binding
protein binding
enzyme activator activity
protein complex binding
cysteine-type endopeptidase activity involved in execution phase of apoptosis