251178

Gene Symbol:

GH2 CSH1 CSH2 CSHL1 GH1

Gene Name:

growth hormone 2

chorionic somatomammotropin hormone 1

chorionic somatomammotropin hormone 2

chorionic somatomammotropin hormone like 1

growth hormone 1

Gene Aliases:

GH-V, GHB2, GHL, GHV, hGH-V

CS-1, CSA, CSMT, GHB3, PL, hCS-1, hCS-A

CS-2, CSB, GHB1, PL, hCS-B

CS-5, CSHP1, CSL, GHB4, hCS-L

GH, GH-N, GHB5, GHN, IGHD1B, hGH-N

Chromosome Location:

Chr.17: 63880212 - 63881942 on Build GRCh38

Chromosome Location:

Chr.17: 63894908 - 63896661 on Build GRCh38

Chromosome Location:

Chr.17: 63872012 - 63873729 on Build GRCh38

Chromosome Location:

Chr.17: 63909597 - 63911328 on Build GRCh38

Chromosome Location:

Chr.17: 63917193 - 63918852 on Build GRCh38

UniGene ID:

Hs.406754

Hs.654390

Hs.654515

Hs.654390

Hs.655229

Species:

Human

Species Specific ID (Flybase ID):

-

-

-

-

-

siRNA Details

Gene Symbol: GH2
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	NM_002059.4	NP_002050.1	2	169
	NM_022556.3	NP_072050.1	2	169
	NM_022557.3	NP_072051.1	2	169
	NM_022558.3	NP_072052.1	2	169
GenBank mRNA	AB451332.1	-	1	28
	AB451477.1	-	1	28
	AF006060.1	-	2	40
	AF006061.1	-	1	28
	AK312194.1	-	2	91
	AU139016.1	-	2	169
	BC020760.1	-	2	90	4720475
	CR541902.1	-	1	28
	CR541924.1	-	1	28
	J03756.1	-	2	89
	M38451.1	-	2	40

Gene Symbol: CSH1
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	NM_001317.5	NP_001308.1	2	178
GenBank mRNA	AK291587.1	-	2	97
	AU134786.2	-	2	178
	BC002717.2	-	2	71	3631916
	BC005921.1	-	2	90	4043768
	BC020756.1	-	2	146	4769769
	BC057768.1	-	2	90	30337725
	BC062775.1	-	2	94	4604848
	BG436049.1	-	2	91
	BT006926.1	-	1	28
	J00118.1	-	2	57

Gene Symbol: CSH2
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	NM_020991.3	NP_066271.1	2	143
	NM_022644.3	NP_072170.1	2	143
	NM_022645.2	NP_072171.1	2	143
GenBank mRNA	BC022044.1	-	2	94	4769046
	BC035965.1	-	2	90	4731880
	BC119748.2	-	2	87	40119242
	V00573.1	-	2	52

Gene Symbol: CSHL1
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	NM_001321068.1	NP_001307997.1	2	160
	NM_001321069.1	NP_001307998.1	2	160
	NM_022579.2	NP_072101.1	2	160
	NM_022581.2	NP_072103.1	2	160
	XM_011524344.1	XP_011522646.1	2	90
GenBank mRNA	AK300190.1	-	2	90
	AX772828.1	-	2	174
	BX426214.2	-	2	73
	DR004701.1	-	2	70

Gene Symbol: GH1
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	NM_000515.4	NP_000506.2	2	104
	NM_022559.3	NP_072053.1	2	104
	NM_022560.3	NP_072054.1	2	104
GenBank mRNA	A00469.1	-	2	67
	AF110644.1	-	2	38
	AF185611.1	-	2	46
	AV749353.1	-	2	104
	AY613431.1	-	2	90
	AY613432.1	-	2	90
	BC062475.1	-	2	69	30393581
	BC075012.2	-	2	55	30915404
	BC075013.2	-	2	55	30915617
	BC090045.1	-	2	71	30394115
	CD108592.1	-	2	70
	M14398.1	-	1	28
	V00519.1	-	2	68

More Information

Additional Information:

This siRNA no longer meets our design criteria. We suggest you choose a different siRNA for this gene or contact Tech Support for more information.

Gene Ontology Categories:

Process(es)

JAK-STAT cascade involved in growth hormone signaling pathway
biological_process
positive regulation of receptor internalization
JAK-STAT cascade
positive regulation of activation of JAK2 kinase activity
positive regulation of phosphatidylinositol 3-kinase signaling
glucose transport
response to estradiol
positive regulation of multicellular organism growth
positive regulation of tyrosine phosphorylation of Stat3 protein
positive regulation of tyrosine phosphorylation of Stat5 protein
positive regulation of MAP kinase activity
positive regulation of insulin-like growth factor receptor signaling pathway
positive regulation of JAK-STAT cascade
positive regulation of peptidyl-tyrosine phosphorylation
growth hormone receptor signaling pathway
bone maturation

Function(s)

hormone activity
metal ion binding
growth hormone receptor binding
prolactin receptor binding
protein binding
growth factor activity