2532

• Gene Symbol: GDNF
• Gene Name: glial cell derived neurotrophic factor
• Gene Aliases: ATF1, ATF2, HFB1-GDNF, HSCR3
• Chromosome Location: Chr.5: 37812677 - 37840044 on Build GRCh38
• UniGene ID: Hs.248114
• Species: Human
• Species Specific ID (Flybase ID): -

siRNA Details

Gene Symbol: GDNF
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	NM_000514.3	NP_000505.1	3	373
	NM_001190468.1	NP_001177397.1	3	393
	NM_001190469.1	NP_001177398.1	3	315
	NM_001278098.1	NP_001265027.1	3	201
	NM_199231.2	NP_954701.1	3	218
	XM_011514030.2	XP_011512332.1	2	86
	XM_017009337.1	XP_016864826.1	3	659
GenBank mRNA	AF053748.1	-	3	373
	AJ001899.1	-	3	218
	AJ001900.1	-	2	207
	AY052832.1	-	2	95
	BC069119.1	-	2	173	7216973
	BC069369.1	-	2	173	7262145
	BC128108.1	-	2	173	40112122
	BC128109.1	-	2	173	40112125
	CR541923.1	-	2	173
	DQ235474.1	-	3	175
	KU178093.1	-	2	173
	KU178094.1	-	2	95

More Information

Additional Information:

This siRNA no longer meets our design criteria. We suggest you choose a different siRNA for this gene or contact Tech Support for more information.

Gene Ontology Categories:

Process(es)

MAPK cascade
metanephros development
branching involved in ureteric bud morphogenesis
neural crest cell migration
organ induction
postsynaptic membrane organization
mesenchymal to epithelial transition involved in metanephros morphogenesis
signal transduction
nervous system development
positive regulation of cell proliferation
adult locomotory behavior
regulation of gene expression
postganglionic parasympathetic fiber development
peristalsis
neuron projection development
positive regulation of monooxygenase activity
positive regulation of dopamine secretion
negative regulation of apoptotic process
negative regulation of neuron apoptotic process
positive regulation of GTPase activity
positive regulation of cell differentiation
positive regulation of transcription from RNA polymerase II promoter
mRNA stabilization
enteric nervous system development
sympathetic nervous system development
regulation of dopamine uptake involved in synaptic transmission
ureteric bud formation
regulation of morphogenesis of a branching structure
positive regulation of ureteric bud formation
positive regulation of mesenchymal to epithelial transition involved in metanephros morphogenesis
positive regulation of branching involved in ureteric bud morphogenesis
regulation of stem cell differentiation
negative regulation of extrinsic apoptotic signaling pathway in absence of ligand

Function(s)

Ras guanyl-nucleotide exchange factor activity
receptor binding
protein binding
growth factor activity
protein homodimerization activity