259863

• Gene Symbol: Map3k11
• Gene Name: mitogen-activated protein kinase kinase kinase 11
• Gene Aliases: Mlk-3, Mlk3, RHOE
• Chromosome Location: Chr.1: 221043119 - 221056420 on Build Rnor_6.0
• UniGene ID: Rn.28235
• Species: Rat
• Species Specific ID (Flybase ID): -

siRNA Details

Gene Symbol: Map3k11
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	NM_001013150.1	NP_001013168.1	8	2208
GenBank mRNA	BC081952.1	-	8	2208	7122664

More Information

Other Species Targeted

This siRNA also targets the following transcripts in Mouse: NM_022012, BC095963, BC047152, BC030928, AK159518.

Gene Ontology Categories:

Process(es)

activation of MAPK activity
protein phosphorylation
microtubule-based process
JNK cascade
activation of JNKK activity
activation of JUN kinase activity
cell death
cell proliferation
peptidyl-tyrosine phosphorylation
positive regulation of apoptotic process
positive regulation of JUN kinase activity
positive regulation of neuron apoptotic process
positive regulation of JNK cascade
protein autophosphorylation

Function(s)

protein serine/threonine kinase activity
JUN kinase kinase kinase activity
MAP kinase kinase kinase activity
protein tyrosine kinase activity
protein binding
ATP binding
mitogen-activated protein kinase kinase binding
mitogen-activated protein kinase kinase kinase binding
identical protein binding
protein homodimerization activity
Rac GTPase binding