30532

• Gene Symbol: FGFR2
• Gene Name: fibroblast growth factor receptor 2
• Gene Aliases: BBDS, BEK, BFR-1, CD332, CEK3, CFD1, ECT1, JWS, K-SAM, KGFR, TK14, TK25
• Chromosome Location: Chr.10: 121478330 - 121598656 on Build GRCh38
• UniGene ID: Hs.533683
• Species: Human
• Species Specific ID (Flybase ID): -

siRNA Details

Gene Symbol: FGFR2
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	NM_000141.4	NP_000132.3	5	1243
	NM_001144913.1	NP_001138385.1	4	746
	NM_001144914.1	NP_001138386.1	4	746
	NM_001144915.1	NP_001138387.1	4	648
	NM_001144916.1	NP_001138388.1	2	692
	NM_001144917.1	NP_001138389.1	5	1243
	NM_001144918.1	NP_001138390.1	3	898
	NM_001144919.1	NP_001138391.1	4	976
	NM_001320658.1	NP_001307587.1	5	1243
	NM_022970.3	NP_075259.4	5	1243
	NM_023029.2	NP_075418.1	3	479
	NR_073009.1		3	898
	XM_006717708.2	XP_006717771.1	5	1441
	XM_006717710.3	XP_006717773.1	5	1441
	XM_006717711.2	XP_006717774.1	3	479
	XM_006717712.2	XP_006717775.1	2	401
	XM_017015920.1	XP_016871409.1	5	1441
	XM_017015921.1	XP_016871410.1	5	1441
	XM_017015922.1	XP_016871411.1	3	479
	XM_017015923.1	XP_016871412.1	3	479
	XM_017015924.1	XP_016871413.1	3	1096
	XM_017015925.1	XP_016871414.1	3	1096
GenBank mRNA	AB030073.1	-	5	1014
	AB030074.1	-	5	1014
	AB030075.1	-	5	1014
	AB030076.1	-	5	1014
	AB030077.1	-	5	1014
	AB030078.1	-	5	1014
	AB084153.1	-	4	596
	AK026508.1	-	4	950
	AK294026.1	-	4	648
	AK308621.1	-	2	692
	BC039243.1	-	3	898	5277896
	EF057068.1	-	3	329
	EU826598.1	-	4	596
	EU826599.1	-	4	596
	EU826600.1	-	4	596
	EU826601.1	-	2	251
	KP192323.1	-	3	413
	KP192324.1	-	3	413
	KP192326.1	-	3	413
	KP192327.1	-	3	413
	KP192328.1	-	4	680
	KP192329.1	-	2	335
	KP192330.1	-	3	413
	KP192331.1	-	4	680
	M55614.1	-	4	608
	M80634.1	-	5	1014
	M87770.1	-	5	869
	M87771.1	-	5	1083
	M87772.1	-	5	871
	M97193.1	-	5	1207
	U11814.1	-	5	854
	X52832.1	-	5	775
	X56191.1	-	4	620
	Z71929.1	-	4	608

More Information

Other Species Targeted

This siRNA also targets the following transcripts in Rat: NM_001109892, NM_012712, NM_001109894, NM_001109895, NM_001109893, and others.
This siRNA also targets the following transcripts in Mouse: NM_201601, NM_010207, EF143325, EF143327, M63503, and others.

Gene Ontology Categories:

Process(es)

negative regulation of transcription from RNA polymerase II promoter
MAPK cascade
angiogenesis
ureteric bud development
in utero embryonic development
epithelial to mesenchymal transition
positive regulation of mesenchymal cell proliferation
outflow tract septum morphogenesis
membranous septum morphogenesis
apoptotic process
cell-cell signaling
axonogenesis
positive regulation of cell proliferation
fibroblast growth factor receptor signaling pathway
regulation of smoothened signaling pathway
post-embryonic development
embryonic pattern specification
organ morphogenesis
regulation of cell fate commitment
positive regulation of phospholipase activity
regulation of phosphatidylinositol 3-kinase signaling
morphogenesis of embryonic epithelium
peptidyl-tyrosine phosphorylation
orbitofrontal cortex development
ventricular zone neuroblast division
pyramidal neuron development
gland morphogenesis
positive regulation of Wnt signaling pathway
bone mineralization
lung development
epithelial cell differentiation
midbrain development
otic vesicle formation
hair follicle morphogenesis
lacrimal gland development
regulation of osteoblast proliferation
multicellular organism growth
organ growth
fibroblast growth factor receptor signaling pathway involved in negative regulation of apoptotic process in bone marrow
fibroblast growth factor receptor signaling pathway involved in hemopoiesis
fibroblast growth factor receptor signaling pathway involved in positive regulation of cell proliferation in bone marrow
fibroblast growth factor receptor signaling pathway involved in orbitofrontal cortex development
phosphatidylinositol-3-phosphate biosynthetic process
regulation of multicellular organism growth
regulation of fibroblast growth factor receptor signaling pathway
inner ear morphogenesis
odontogenesis
positive regulation of MAPK cascade
positive regulation of GTPase activity
cell fate commitment
regulation of osteoblast differentiation
positive regulation of cell cycle
positive regulation of transcription from RNA polymerase II promoter
protein autophosphorylation
phosphatidylinositol phosphorylation
phosphatidylinositol-mediated signaling
lung alveolus development
mesodermal cell differentiation
embryonic digestive tract morphogenesis
embryonic organ morphogenesis
digestive tract development
embryonic organ development
reproductive structure development
positive regulation of smooth muscle cell proliferation
embryonic cranial skeleton morphogenesis
skeletal system morphogenesis
epidermis morphogenesis
branching morphogenesis of a nerve
mesenchymal cell differentiation
positive regulation of epithelial cell proliferation
negative regulation of epithelial cell proliferation
regulation of smooth muscle cell differentiation
positive regulation of cell division
ventricular cardiac muscle tissue morphogenesis
positive regulation of cardiac muscle cell proliferation
limb bud formation
bone development
bone morphogenesis
branching involved in prostate gland morphogenesis
branching involved in salivary gland morphogenesis
bud elongation involved in lung branching
lung lobe morphogenesis
lung-associated mesenchyme development
positive regulation of epithelial cell proliferation involved in lung morphogenesis
prostate gland morphogenesis
prostate epithelial cord elongation
prostate epithelial cord arborization involved in prostate glandular acinus morphogenesis
squamous basal epithelial stem cell differentiation involved in prostate gland acinus development
fibroblast growth factor receptor signaling pathway involved in mammary gland specification
lateral sprouting from an epithelium
mammary gland bud formation
epithelial cell proliferation involved in salivary gland morphogenesis
branch elongation involved in salivary gland morphogenesis
branching involved in labyrinthine layer morphogenesis
regulation of branching involved in prostate gland morphogenesis
regulation of morphogenesis of a branching structure
mesenchymal cell differentiation involved in lung development
mesenchymal cell proliferation involved in lung development
regulation of ERK1 and ERK2 cascade
positive regulation of ERK1 and ERK2 cascade
positive regulation of canonical Wnt signaling pathway

Function(s)

protein tyrosine kinase activity
fibroblast growth factor-activated receptor activity
Ras guanyl-nucleotide exchange factor activity
protein binding
ATP binding
heparin binding
1-phosphatidylinositol-3-kinase activity
fibroblast growth factor binding
protein homodimerization activity
phosphatidylinositol-4,5-bisphosphate 3-kinase activity