3376

• Gene Symbol: NKX6-1
• Gene Name: NK6 homeobox 1
• Gene Aliases: NKX6.1, NKX6A
• Chromosome Location: Chr.4: 84493283 - 84498234 on Build GRCh38
• UniGene ID: Hs.546270
• Species: Human
• Species Specific ID (Flybase ID): -

siRNA Details

Gene Symbol: NKX6-1
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	NM_006168.2	NP_006159.2	2	690

More Information

Other Species Targeted

This siRNA also targets the following transcripts in Rat: NM_031737, AF004431.
This siRNA also targets the following transcripts in Mouse: NM_144955, BC138020, AF357883, BC138019.

Gene Ontology Categories:

Process(es)

negative regulation of transcription from RNA polymerase II promoter
neuron migration
transcription from RNA polymerase II promoter
smoothened signaling pathway
organ morphogenesis
regulation of transcription from RNA polymerase II promoter involved in spinal cord motor neuron fate specification
regulation of transcription from RNA polymerase II promoter involved in ventral spinal cord interneuron specification
regulation of axon extension
pancreas development
positive regulation of insulin secretion
response to nicotine
response to drug
type B pancreatic cell proliferation
positive regulation of neuron differentiation
negative regulation of glial cell differentiation
positive regulation of glial cell differentiation
positive regulation of transcription from RNA polymerase II promoter
oligodendrocyte differentiation
positive regulation of sequence-specific DNA binding transcription factor activity
detection of glucose
cellular response to cytokine stimulus
cellular response to peptide hormone stimulus
type B pancreatic cell maturation
positive regulation of type B pancreatic cell development
regulation of neuron migration

Function(s)

RNA polymerase II core promoter proximal region sequence-specific DNA binding
transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding
chromatin binding