34573

• Gene Symbol: BTRC
• Gene Name: beta-transducin repeat containing E3 ubiquitin protein ligase
• Gene Aliases: BETA-TRCP, FBW1A, FBXW1, FBXW1A, FWD1, bTrCP, bTrCP1, betaTrCP
• Chromosome Location: Chr.10: 101353808 - 101557321 on Build GRCh38
• UniGene ID: Hs.643802
• Species: Human
• Species Specific ID (Flybase ID): -

siRNA Details

Gene Symbol: BTRC
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	NM_001256856.1	NP_001243785.1	14	3145
	NM_003939.4	NP_003930.1	14	3115
	NM_033637.3	NP_378663.1	15	3223
	XM_006718054.2	XP_006718117.1	15	3523
	XM_011540320.2	XP_011538622.1	12	2959
	XM_017016870.1	XP_016872359.1	14	3445
	XM_017016871.1	XP_016872360.1	15	3114
	XM_017016872.1	XP_016872361.1	15	3286
	XM_017016873.1	XP_016872362.1	15	3142
	XM_017016874.1	XP_016872363.1	13	3037
GenBank mRNA	BC006204.2	-	1	185
	CR749295.1	-	14	3076

More Information

Additional Information:

This siRNA no longer meets our design criteria. We suggest you choose a different siRNA for this gene or contact Tech Support for more information.

Gene Ontology Categories:

Process(es)

G2/M transition of mitotic cell cycle
protein polyubiquitination
stimulatory C-type lectin receptor signaling pathway
protein dephosphorylation
ubiquitin-dependent protein catabolic process
signal transduction
viral process
Wnt signaling pathway
protein ubiquitination
SCF-dependent proteasomal ubiquitin-dependent protein catabolic process
protein destabilization
mammary gland epithelial cell proliferation
NIK/NF-kappaB signaling
Fc-epsilon receptor signaling pathway
regulation of circadian rhythm
positive regulation of circadian rhythm
regulation of I-kappaB kinase/NF-kappaB signaling
proteasome-mediated ubiquitin-dependent protein catabolic process
negative regulation of sequence-specific DNA binding transcription factor activity
positive regulation of proteolysis
negative regulation of smoothened signaling pathway
negative regulation of transcription, DNA-templated
positive regulation of transcription, DNA-templated
rhythmic process
T cell receptor signaling pathway
stress-activated MAPK cascade
positive regulation of ubiquitin-protein ligase activity involved in regulation of mitotic cell cycle transition
branching involved in mammary gland duct morphogenesis
regulation of canonical Wnt signaling pathway
regulation of proteasomal protein catabolic process
cellular response to organic cyclic compound

Function(s)

ubiquitin-protein transferase activity
protein binding
beta-catenin binding
ligase activity
protein phosphorylated amino acid binding
protein dimerization activity
ubiquitin protein ligase activity