34674

• Gene Symbol: MDM2
• Gene Name: MDM2 proto-oncogene
• Gene Aliases: ACTFS, HDMX, hdm2
• Chromosome Location: Chr.12: 68808149 - 68845544 on Build GRCh38
• UniGene ID: Hs.484551
• Species: Human
• Species Specific ID (Flybase ID): -

siRNA Details

Gene Symbol: MDM2
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	NM_001145337.2	NP_001138809.1	11	3821
	NM_001145339.2	NP_001138811.1	9	4047
	NM_001145340.2	NP_001138812.1	5	3374
	NM_001278462.1	NP_001265391.1	6	3452
	NM_002392.5	NP_002383.2	11	4212
	XM_005268872.4	XP_005268929.1	11	4140
	XM_006719399.3	XP_006719462.1	9	3795
	XM_006719400.3	XP_006719463.1	10	4101
GenBank mRNA	BC065505.1	-	1	507
	BC107414.1	-	1	756

More Information

Additional Information:

This siRNA no longer meets our design criteria. We suggest you choose a different siRNA for this gene or contact Tech Support for more information.

Gene Ontology Categories:

Process(es)

negative regulation of transcription from RNA polymerase II promoter
blood vessel development
blood vessel remodeling
regulation of heart rate
atrioventricular valve morphogenesis
endocardial cushion morphogenesis
ventricular septum development
atrial septum development
protein complex assembly
DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest
traversing start control point of mitotic cell cycle
positive regulation of cell proliferation
response to toxic substance
response to carbohydrate
response to iron ion
positive regulation of gene expression
negative regulation of protein processing
viral process
protein ubiquitination
protein sumoylation
peptidyl-lysine modification
protein destabilization
response to magnesium ion
positive regulation of proteasomal ubiquitin-dependent protein catabolic process
protein localization to nucleus
regulation of protein catabolic process
response to cocaine
response to drug
protein ubiquitination involved in ubiquitin-dependent protein catabolic process
negative regulation of cysteine-type endopeptidase activity involved in apoptotic process
response to morphine
negative regulation of DNA damage response, signal transduction by p53 class mediator
establishment of protein localization
response to ether
negative regulation of transcription, DNA-templated
positive regulation of mitotic cell cycle
response to antibiotic
positive regulation of protein export from nucleus
response to steroid hormone
cardiac septum morphogenesis
cellular response to hydrogen peroxide
negative regulation of cell cycle arrest
cellular response to antibiotic
cellular response to vitamin B1
cellular response to alkaloid
cellular response to growth factor stimulus
cellular response to peptide hormone stimulus
cellular response to estrogen stimulus
cellular response to hypoxia
cellular response to UV-C
regulation of signal transduction by p53 class mediator
negative regulation of signal transduction by p53 class mediator

Function(s)

p53 binding
ubiquitin-protein transferase activity
protein binding
zinc ion binding
ligase activity
SUMO transferase activity
enzyme binding
ubiquitin protein ligase binding
identical protein binding
peroxisome proliferator activated receptor binding
ubiquitin protein ligase activity
scaffold protein binding