45446

• Gene Symbol: MESP1
• Gene Name: mesoderm posterior bHLH transcription factor 1
• Gene Aliases: bHLHc5
• Chromosome Location: Chr.15: 89734772 - 89751309 on Build GRCh38
• UniGene ID: Hs.447531
• Species: Human
• Species Specific ID (Flybase ID): -

siRNA Details

Gene Symbol: MESP1
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	NM_018670.3	NP_061140.1	2	955
GenBank mRNA	AL357533.1	-	2	508
	AL357534.1	-	2	486
	AL357535.1	-	1	128
	AL357570.1	-	2	402
	AL357571.1	-	2	775
	BC006219.1	-	2	963	3944350
	BP212916.1	-	2	525

More Information

Gene Ontology Categories:

Process(es)

heart looping
secondary heart field specification
embryonic heart tube morphogenesis
cardiac atrium formation
cardiac ventricle formation
sinus venosus morphogenesis
growth involved in heart morphogenesis
cardioblast anterior-lateral migration
transcription from RNA polymerase II promoter
Notch signaling pathway
gastrulation
mesodermal cell migration
neurogenesis
signal transduction involved in regulation of gene expression
positive regulation of Notch signaling pathway involved in heart induction
negative regulation of mesodermal cell fate specification
negative regulation of endodermal cell fate specification
endothelial cell differentiation
positive regulation of Notch signaling pathway
negative regulation of transcription, DNA-templated
positive regulation of transcription, DNA-templated
positive regulation of transcription from RNA polymerase II promoter
lateral mesoderm development
positive regulation of striated muscle cell differentiation
cardiac muscle cell differentiation
cardiac cell fate determination
sinoatrial node cell differentiation
cardiac vascular smooth muscle cell differentiation
cardioblast migration to the midline involved in heart field formation
positive regulation of hepatocyte differentiation
positive regulation of heart induction by negative regulation of canonical Wnt signaling pathway

Function(s)

RNA polymerase II core promoter proximal region sequence-specific DNA binding
transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding
transcription factor activity, sequence-specific DNA binding
enhancer binding
transcription regulatory region DNA binding
protein dimerization activity