46152

• Gene Symbol: CCL19
• Gene Name: C-C motif chemokine ligand 19
• Gene Aliases: CKb11, ELC, MIP-3b, MIP3B, SCYA19
• Chromosome Location: Chr.9: 34689570 - 34691277 on Build GRCh38
• UniGene ID: Hs.50002
• Species: Human
• Species Specific ID (Flybase ID): -

siRNA Details

Gene Symbol: CCL19
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	NM_006274.2	NP_006265.1	2	228
GenBank mRNA	AB000887.1	-	2	228
	AK311945.1	-	2	227
	AX772806.1	-	2	227
	BC027968.1	-	2	214	5225849
	CR456868.1	-	2	90
	U77180.1	-	2	90
	U88321.1	-	2	209

More Information

Other Species Targeted

This siRNA also targets the following transcripts in Rat: NM_001108661.
This siRNA also targets the following transcripts in Mouse: NM_011888, AF059208, BC051472, AK156269, BC025130, and others.

Gene Ontology Categories:

Process(es)

establishment of T cell polarity
immunological synapse formation
dendritic cell chemotaxis
myeloid dendritic cell chemotaxis
monocyte chemotaxis
positive regulation of dendritic cell antigen processing and presentation
cellular calcium ion homeostasis
inflammatory response
immune response
cell communication
G-protein coupled receptor signaling pathway
activation of JUN kinase activity
response to virus
positive regulation of glycoprotein biosynthetic process
T cell costimulation
positive regulation of interleukin-12 production
positive regulation of tumor necrosis factor production
response to prostaglandin E
positive regulation of T cell proliferation
positive regulation of NF-kappaB import into nucleus
positive regulation of I-kappaB kinase/NF-kappaB signaling
positive regulation of GTPase activity
positive regulation of phosphatidylinositol 3-kinase activity
positive regulation of T-helper 1 cell differentiation
positive regulation of endocytosis
positive regulation of protein kinase activity
positive regulation of JNK cascade
lymphocyte chemotaxis
positive regulation of receptor-mediated endocytosis
cell maturation
positive regulation of interleukin-1 beta secretion
positive regulation of chemotaxis
release of sequestered calcium ion into cytosol
positive regulation of protein kinase B signaling
regulation of cell projection assembly
chemokine-mediated signaling pathway
positive regulation of ERK1 and ERK2 cascade
cellular response to interferon-gamma
cellular response to interleukin-1
cellular response to tumor necrosis factor
response to nitric oxide
interleukin-12 secretion
positive regulation of neutrophil chemotaxis
mature conventional dendritic cell differentiation
cellular response to virus
negative regulation of leukocyte apoptotic process
positive regulation of cell motility
positive regulation of dendritic cell dendrite assembly

Function(s)

chemokine activity
CCR7 chemokine receptor binding
CCR10 chemokine receptor binding
chemokine receptor binding
CCR chemokine receptor binding