50076

• Gene Symbol: Erbb3
• Gene Name: erb-b2 receptor tyrosine kinase 3
• Gene Aliases: nuc-ErbB3
• Chromosome Location: Chr.7: 2991016 - 3010312 on Build Rnor_6.0
• UniGene ID: Rn.10228
• Species: Rat
• Species Specific ID (Flybase ID): -

siRNA Details

Gene Symbol: Erbb3
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	NM_017218.3	NP_058914.2	28	3722
GenBank mRNA	GU598254.1	-	6	1181
	U29339.2	-	28	3722

More Information

Other Species Targeted

This siRNA also targets the following transcripts in Human: NM_001982, BC082992, AK295650, BC002706, M34309, and others.
This siRNA also targets the following transcripts in Mouse: NM_010153, AY686636, BC049279, BC029028, BC106091, and others.

Gene Ontology Categories:

Process(es)

endocardial cushion development
negative regulation of cell adhesion
signal transduction
transmembrane receptor protein tyrosine kinase signaling pathway
epidermal growth factor receptor signaling pathway
axonogenesis
peripheral nervous system development
skeletal muscle tissue development
circadian rhythm
response to wounding
negative regulation of signal transduction
Schwann cell differentiation
phosphatidylinositol 3-kinase signaling
peptidyl-tyrosine phosphorylation
cranial nerve development
signal transduction by protein phosphorylation
cellular response to insulin stimulus
regulation of cell proliferation
odontogenesis
response to drug
negative regulation of neuron apoptotic process
tongue development
positive regulation of glucose import
negative regulation of secretion
neuron apoptotic process
mammary gland involution
positive regulation of protein tyrosine kinase activity
positive regulation of calcineurin-NFAT signaling cascade
extrinsic apoptotic signaling pathway in absence of ligand

Function(s)

protein tyrosine kinase activity
transmembrane receptor protein tyrosine kinase activity
receptor signaling protein tyrosine kinase activity
ATP binding
growth factor binding
protein tyrosine kinase activator activity
neuregulin receptor activity
neuregulin binding
identical protein binding
protein heterodimerization activity