50215

Gene Symbol:

Hsd3b6 Hsd3b Hsd3b1 LOC100911154

Gene Name:

hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 6

3 beta-hydroxysteroid dehydrogenase/delta-5-delta-4 isomerase type II

hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 1

3 beta-hydroxysteroid dehydrogenase/Delta 5-->4-isomerase type 4-like

Gene Aliases:

Hsd3b1

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Chromosome Location:

Chr.2: 202341417 - 202350874 on Build Rnor_6.0

Chromosome Location:

Chr.2: 200756557 - 200762492 on Build Rnor_6.0

Chromosome Location:

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Chromosome Location:

Chr.2: 200712893 - 200722448 on Build Rnor_6.0

UniGene ID:

Rn.109394

Rn.128814

Rn.128814

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Species:

Rat

Species Specific ID (Flybase ID):

-

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siRNA Details

Gene Symbol: Hsd3b6
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	NM_017265.4	NP_058961.4	4	1267
GenBank mRNA	BC089937.1	-	4	1267	7309637
	L17138.1	-	3	1105

Gene Symbol: Hsd3b
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	NM_001042619.1	NP_001036084.1	4	1201
GenBank mRNA	M38179.1	-	4	1201

Gene Symbol: Hsd3b1
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	NM_001007719.3	NP_001007720.3	6	1201
GenBank mRNA	BC086578.1	-	6	1201	7306702
	DQ515797.1	-	1	373
	M38178.1	-	5	1220

Gene Symbol: LOC100911154
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	XM_003749361.2	XP_003749409.1	5	1286

More Information

Other Species Targeted

This siRNA also targets the following transcripts in Human: NM_000198, NM_001166120, AF252254, BC131488, AK313413, and others.
This siRNA also targets the following transcripts in Mouse: NM_001111336, NM_001161743, NM_013821, NM_001161742, NM_001161744, and others.

Gene Ontology Categories:

Process(es)

steroid biosynthetic process
C21-steroid hormone biosynthetic process
androgen biosynthetic process
response to lead ion
hippocampus development
Leydig cell differentiation
response to gonadotropin
negative regulation of iron ion transport
response to cadmium ion
response to corticosterone
oxidation-reduction process
organic acid metabolic process
progesterone biosynthetic process
estrogen biosynthetic process
steroid metabolic process
C21-steroid hormone metabolic process
male gonad development
female gonad development
response to herbicide
response to organic substance
response to metal ion
response to lithium ion
response to organic cyclic compound
response to activity
diterpenoid metabolic process
insecticide metabolic process
biphenyl metabolic process
dibenzo-p-dioxin metabolic process
phenol-containing compound metabolic process
toluene metabolic process
adrenal gland development
ovulation
granulocyte differentiation
response to nutrient levels
response to estradiol
cellular response to insulin stimulus
response to vitamin E
response to L-ascorbic acid
response to drug
response to alkaloid
cellular response to fibroblast growth factor stimulus
response to ethanol
phosphatidylcholine metabolic process
response to arsenic-containing substance
response to calcium ion
maternal process involved in female pregnancy
response to fungicide
testosterone biosynthetic process
cellular response to hydrogen peroxide
response to fatty acid
cellular response to antibiotic
cellular response to mercury ion
cellular response to cAMP
cellular response to glucose stimulus
cellular response to gonadotropin stimulus
cellular response to follicle-stimulating hormone stimulus
cellular response to luteinizing hormone stimulus
cellular response to methylmercury
cellular response to dexamethasone stimulus
cellular response to transforming growth factor beta stimulus

Function(s)

3-beta-hydroxy-delta5-steroid dehydrogenase activity
steroid delta-isomerase activity
isomerase activity
testosterone dehydrogenase [NAD(P)] activity
steroid binding
dihydrotestosterone 17-beta-dehydrogenase activity
NAD binding