50824

• Gene Symbol: Men1
• Gene Name: multiple endocrine neoplasia I
• Gene Aliases: menin
• Chromosome Location: Chr.1: 221704408 - 221710343 on Build Rnor_6.0
• UniGene ID: Rn.6775
• Species: Rat
• Species Specific ID (Flybase ID): -

siRNA Details

Gene Symbol: Men1
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	NM_019208.3	NP_062081.1	7	1478
	XM_006230769.2	XP_006230831.1	8	1196
	XM_006230770.2	XP_006230832.1	8	1287
	XM_006230771.2	XP_006230833.1	8	1197
	XM_006230772.2	XP_006230834.1	8	1255
GenBank mRNA	AB023400.1	-	7	1545
	AF130369.1	-	7	1453
	AF130370.1	-	7	1098

More Information

Gene Ontology Categories:

Process(es)

negative regulation of transcription from RNA polymerase II promoter
MAPK cascade
mitotic cell cycle
ossification
leukocyte homeostasis
negative regulation of protein phosphorylation
osteoblast fate commitment
osteoblast development
type B pancreatic cell differentiation
chromatin remodeling
transcription, DNA-templated
cellular response to DNA damage stimulus
cell cycle arrest
brain development
negative regulation of cell proliferation
response to UV
response to gamma radiation
negative regulation of cell-substrate adhesion
histone methylation
hemopoiesis
positive regulation of transforming growth factor beta receptor signaling pathway
positive regulation of histone methylation
positive regulation of protein binding
regulation of activin receptor signaling pathway
histone lysine methylation
positive regulation of apoptotic process
positive regulation of cysteine-type endopeptidase activity involved in apoptotic process
negative regulation of sequence-specific DNA binding transcription factor activity
positive regulation of cell differentiation
negative regulation of osteoblast differentiation
positive regulation of osteoblast differentiation
negative regulation of cyclin-dependent protein serine/threonine kinase activity
negative regulation of cell cycle
negative regulation of transcription, DNA-templated
positive regulation of transcription, DNA-templated
positive regulation of transcription from RNA polymerase II promoter
negative regulation of JNK cascade
negative regulation of organ growth
decidualization
embryonic skeletal system morphogenesis
negative regulation of epithelial cell proliferation
positive regulation of cell division
negative regulation of telomerase activity
palate development
maternal process involved in female pregnancy
regulation of type B pancreatic cell proliferation
cellular response to glucose stimulus
cellular response to peptide hormone stimulus
response to transforming growth factor beta
negative regulation of cell cycle G1/S phase transition

Function(s)

four-way junction DNA binding
Y-form DNA binding
molecular_function
DNA binding
chromatin binding
double-stranded DNA binding
histone-lysine N-methyltransferase activity
protein binding, bridging
sequence-specific DNA binding
transcription regulatory region DNA binding
protein N-terminus binding
R-SMAD binding