52220

• Gene Symbol: Slit2
• Gene Name: slit homolog 2 (Drosophila)
• Gene Aliases: -
• Chromosome Location: Chr.14: 66831848 - 67170361 on Build Rnor_6.0
• UniGene ID: Rn.146652
• Species: Rat
• Species Specific ID (Flybase ID): -

siRNA Details

Gene Symbol: Slit2
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	NM_022632.2	NP_072154.2	19	2557
	XM_008770210.1	XP_008768432.1	16	1692

More Information

Other Species Targeted

This siRNA also targets the following transcripts in Mouse: NM_178804, BC059267, AK220505, BC145487, AF144628, and others.

Gene Ontology Categories:

Process(es)

metanephros development
ureteric bud development
in utero embryonic development
negative regulation of protein phosphorylation
cell migration involved in sprouting angiogenesis
negative regulation of leukocyte chemotaxis
chemotaxis
axonogenesis
axon guidance
brain development
motor neuron axon guidance
negative regulation of cell proliferation
negative regulation of lamellipodium assembly
negative regulation of endothelial cell migration
negative regulation of gene expression
negative regulation of smooth muscle cell migration
single organismal cell-cell adhesion
spinal cord development
olfactory bulb development
chemorepulsion involved in embryonic olfactory bulb interneuron precursor migration
chemorepulsion involved in postnatal olfactory bulb interneuron migration
corticospinal neuron axon guidance through spinal cord
telencephalon cell migration
cell differentiation
negative regulation of cell growth
negative regulation of cell migration
negative regulation of axon extension
negative regulation of actin filament polymerization
retinal ganglion cell axon guidance
response to nutrient levels
cellular response to hormone stimulus
dorsal/ventral axon guidance
Roundabout signaling pathway
follicle-stimulating hormone signaling pathway
positive regulation of apoptotic process
negative regulation of catalytic activity
negative regulation of vascular permeability
branching morphogenesis of an epithelial tube
neuron projection morphogenesis
axon extension involved in axon guidance
negative regulation of inflammatory response
negative chemotaxis
induction of negative chemotaxis
negative regulation of small GTPase mediated signal transduction
response to cortisol
mammary gland duct morphogenesis
mammary duct terminal end bud growth
apoptotic process involved in luteolysis
negative regulation of chemokine-mediated signaling pathway
cellular response to heparin
negative regulation of smooth muscle cell chemotaxis
negative regulation of mononuclear cell migration
negative regulation of neutrophil chemotaxis
negative regulation of monocyte chemotaxis
negative regulation of retinal ganglion cell axon guidance
negative regulation of cellular response to growth factor stimulus

Function(s)

follicle-stimulating hormone receptor activity
GTPase inhibitor activity
calcium ion binding
protein binding
heparin binding
identical protein binding
protein homodimerization activity
laminin-1 binding
proteoglycan binding
heparan sulfate proteoglycan binding
chemorepellent activity
Roundabout binding