53302

• Gene Symbol: Msh2
• Gene Name: mutS homolog 2
• Gene Aliases: -
• Chromosome Location: Chr.6: 11215951 - 11274916 on Build Rnor_6.0
• UniGene ID: Rn.3174
• Species: Rat
• Species Specific ID (Flybase ID): -

siRNA Details

Gene Symbol: Msh2
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	NM_031058.1	NP_112320.1	6, 7	1072
GenBank mRNA	BC161846.1	-	6, 7	1088	9029023
	X93591.1	-	6, 7	1072

More Information

Gene Ontology Categories:

Process(es)

meiotic mismatch repair
in utero embryonic development
somatic recombination of immunoglobulin genes involved in immune response
oxidative phosphorylation
DNA repair
mismatch repair
postreplication repair
double-strand break repair
meiotic gene conversion
cellular response to DNA damage stimulus
cell cycle arrest
germ cell development
spermatogenesis
determination of adult lifespan
male gonad development
intrinsic apoptotic signaling pathway in response to DNA damage
response to X-ray
response to UV-B
response to organic cyclic compound
somatic hypermutation of immunoglobulin genes
somatic recombination of immunoglobulin gene segments
B cell mediated immunity
B cell differentiation
intra-S DNA damage checkpoint
response to drug
intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator
response to amino acid
negative regulation of neuron apoptotic process
maintenance of DNA repeat elements
negative regulation of reciprocal meiotic recombination
isotype switching
negative regulation of DNA recombination
positive regulation of helicase activity

Function(s)

magnesium ion binding
four-way junction DNA binding
Y-form DNA binding
heteroduplex DNA loop binding
double-strand/single-strand DNA junction binding
DNA binding
damaged DNA binding
double-stranded DNA binding
single-stranded DNA binding
ATP binding
protein C-terminus binding
DNA-dependent ATPase activity
ATPase activity
centromeric DNA binding
enzyme binding
protein kinase binding
mismatched DNA binding
guanine/thymine mispair binding
single base insertion or deletion binding
dinucleotide insertion or deletion binding
single guanine insertion binding
single thymine insertion binding
dinucleotide repeat insertion binding
oxidized purine DNA binding
MutLalpha complex binding
protein homodimerization activity
ADP binding