53623

• Gene Symbol: Ccl2
• Gene Name: chemokine (C-C motif) ligand 2
• Gene Aliases: MCP-1, Scya2, Sigje
• Chromosome Location: Chr.10: 69412065 - 69413863 on Build Rnor_6.0
• UniGene ID: Rn.4772
• Species: Rat
• Species Specific ID (Flybase ID): -

siRNA Details

Gene Symbol: Ccl2
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	NM_031530.1	NP_113718.1	2	256
GenBank mRNA	AF058786.1	-	2	256
	M57441.1	-	2	220

More Information

Other Species Targeted

This siRNA also targets the following transcripts in Mouse: NM_011333, AK153520, AF065930, AK132590, BC145869, and others.

Gene Ontology Categories:

Process(es)

MAPK cascade
response to hypoxia
positive regulation of leukocyte mediated cytotoxicity
positive regulation of endothelial cell proliferation
leukocyte migration involved in inflammatory response
monocyte chemotaxis
positive regulation of leukocyte migration
positive regulation of cellular extravasation
cellular calcium ion homeostasis
inflammatory response
cytoskeleton organization
transforming growth factor beta receptor signaling pathway
aging
glial cell migration
regulation of cell shape
response to heat
response to wounding
response to mechanical stimulus
response to bacterium
response to gamma radiation
regulation of vascular endothelial growth factor production
positive regulation of macrophage chemotaxis
response to activity
negative regulation of angiogenesis
cytokine-mediated signaling pathway
positive regulation of cell-cell adhesion
neutrophil chemotaxis
organ regeneration
lipopolysaccharide-mediated signaling pathway
response to lipopolysaccharide
response to progesterone
positive regulation of tumor necrosis factor production
cellular response to insulin stimulus
positive regulation of collagen biosynthetic process
response to vitamin B3
negative regulation of glial cell apoptotic process
helper T cell extravasation
cellular response to drug
cellular response to macrophage colony-stimulating factor stimulus
cellular response to platelet-derived growth factor stimulus
chemokinesis
response to drug
response to amino acid
protein kinase B signaling
negative regulation of neuron apoptotic process
astrocyte cell migration
cellular response to fibroblast growth factor stimulus
response to ethanol
positive regulation of cell adhesion
response to antibiotic
vascular endothelial growth factor receptor signaling pathway
macrophage chemotaxis
lymphocyte chemotaxis
positive regulation of synaptic transmission
positive regulation of T cell activation
response to glucocorticoid
positive regulation of nitric-oxide synthase biosynthetic process
maternal process involved in female pregnancy
maternal process involved in parturition
chemokine-mediated signaling pathway
cellular response to lipopolysaccharide
cellular response to retinoic acid
cellular response to ATP
cellular response to interferon-gamma
cellular response to interleukin-1
cellular response to interleukin-6
cellular response to tumor necrosis factor
cellular response to lipoprotein particle stimulus
cellular response to high density lipoprotein particle stimulus
cellular response to organic cyclic compound
cellular response to dexamethasone stimulus
positive regulation of monocyte chemotaxis
positive regulation of immune complex clearance by monocytes and macrophages
positive regulation of calcium ion import
positive regulation of protein targeting to membrane
positive regulation of apoptotic cell clearance
negative regulation of natural killer cell chemotaxis

Function(s)

G-protein coupled receptor binding
chemokine activity
heparin binding
CCR2 chemokine receptor binding