54408

Gene Symbol:

Hspa1b Hspa1a

Gene Name:

heat shock 70kD protein 1B (mapped)

heat shock 70kD protein 1A

Gene Aliases:

Hsp70-2, Hsp72, Hspa2

HSP72, Hsp70-1, Hspa1, Hspa1b

Chromosome Location:

Chr.20: 4875834 - 4881751 on Build Rnor_6.0

Chromosome Location:

Chr.20: 2699707 - 2701980 on Build Rnor_6.0

UniGene ID:

Rn.1950

Rn.1950

Species:

Rat

Species Specific ID (Flybase ID):

-

-

siRNA Details

Gene Symbol: Hspa1b
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	NM_212504.1	NP_997669.1	1	2464

Gene Symbol: Hspa1a
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	NM_031971.2	NP_114177.2		1561
GenBank mRNA	L16764.1	-		491

More Information

Other Species Targeted

This siRNA also targets the following transcripts in Mouse: NM_010478, NM_010479, BC032044, AK159139, BC151107, and others.

Gene Ontology Categories:

Process(es)

telomere maintenance
response to ischemia
DNA repair
mRNA catabolic process
response to unfolded protein
negative regulation of cell proliferation
response to radiation
response to heat
response to mechanical stimulus
regulation of cell death
neuron differentiation
negative regulation of cell growth
negative regulation of protein ubiquitination
cellular response to heat
protein refolding
negative regulation of apoptotic process
response to ethanol
positive regulation of erythrocyte differentiation
positive regulation of neuron differentiation
negative regulation of cell death
cellular heat acclimation
negative regulation of inclusion body assembly
negative regulation of extrinsic apoptotic signaling pathway in absence of ligand
positive regulation of T cell mediated cytotoxicity
defense response
binding of sperm to zona pellucida
negative regulation of myeloid cell apoptotic process
negative regulation of cysteine-type endopeptidase activity involved in apoptotic process
negative regulation of vasoconstriction

Function(s)

G-protein coupled receptor binding
molecular_function
double-stranded RNA binding
protein binding
ATP binding
ATPase activity
enzyme binding
heat shock protein binding
ubiquitin protein ligase binding
ATPase activity, coupled
protein binding involved in protein folding
poly(A) RNA binding
protein N-terminus binding
unfolded protein binding
protease binding
NF-kappaB binding