54577

• Gene Symbol: Wfs1
• Gene Name: Wolfram syndrome 1 (wolframin)
• Gene Aliases: -
• Chromosome Location: Chr.14: 78640707 - 78665224 on Build Rnor_6.0
• UniGene ID: Rn.229139
• Species: Rat
• Species Specific ID (Flybase ID): -

siRNA Details

Gene Symbol: Wfs1
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	NM_031823.1	NP_114011.1	7	1997
GenBank mRNA	AF136378.1	-	7	1997

More Information

Gene Ontology Categories:

Process(es)

kidney development
renal water homeostasis
visual perception
sensory perception of sound
ER-associated ubiquitin-dependent protein catabolic process
endoplasmic reticulum unfolded protein response
pancreas development
positive regulation of protein ubiquitination
endoplasmic reticulum calcium ion homeostasis
response to endoplasmic reticulum stress
olfactory behavior
glucose homeostasis
negative regulation of programmed cell death
negative regulation of sequence-specific DNA binding transcription factor activity
negative regulation of neuron apoptotic process
positive regulation of proteolysis
positive regulation of growth
protein stabilization
neurological system process
positive regulation of protein metabolic process
positive regulation of calcium ion transport
calcium ion homeostasis
polyubiquitinated misfolded protein transport
negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway
negative regulation of type B pancreatic cell apoptotic process

Function(s)

transporter activity
calmodulin binding
ubiquitin protein ligase binding
activating transcription factor binding
calcium-dependent protein binding
ATPase binding