54595

Gene Symbol:

Hspa1l Hspa1a Hspa1b

Gene Name:

heat shock protein 1-like

heat shock 70kD protein 1A

heat shock 70kD protein 1B (mapped)

Gene Aliases:

Hsp70-3

HSP72, Hsp70-1, Hspa1, Hspa1b

Hsp70-2, Hsp72, Hspa2

Chromosome Location:

Chr.20: 4959294 - 4965191 on Build Rnor_6.0

Chromosome Location:

Chr.20: 2699707 - 2701980 on Build Rnor_6.0

Chromosome Location:

Chr.20: 4875834 - 4881751 on Build Rnor_6.0

UniGene ID:

Rn.187184

Rn.1950

Rn.1950

Species:

Rat

Species Specific ID (Flybase ID):

-

-

-

siRNA Details

Gene Symbol: Hspa1l
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	NM_212546.4	NP_997711.1	2	915
GenBank mRNA	BC108294.1	-	1	777	7111250
	BC108297.1	-	2	915	7115041

Gene Symbol: Hspa1a
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	NM_031971.2	NP_114177.2		1995
GenBank mRNA	L16764.1	-		925

Gene Symbol: Hspa1b
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	NM_212504.1	NP_997669.1	1	2898

More Information

Other Species Targeted

This siRNA also targets the following transcripts in Mouse: NM_010478, NM_013558, NM_010479, M12571, AK159139, and others.

Gene Ontology Categories:

Process(es)

binding of sperm to zona pellucida
biological_process
protein refolding
positive regulation of T cell mediated cytotoxicity
mRNA catabolic process
defense response
response to unfolded protein
negative regulation of cell proliferation
response to heat
regulation of cell death
negative regulation of cell growth
negative regulation of protein ubiquitination
negative regulation of myeloid cell apoptotic process
cellular response to heat
negative regulation of apoptotic process
negative regulation of cysteine-type endopeptidase activity involved in apoptotic process
positive regulation of erythrocyte differentiation
negative regulation of vasoconstriction
negative regulation of cell death
cellular heat acclimation
negative regulation of inclusion body assembly
negative regulation of extrinsic apoptotic signaling pathway in absence of ligand
telomere maintenance
response to ischemia
DNA repair
response to radiation
response to mechanical stimulus
neuron differentiation
response to ethanol
positive regulation of neuron differentiation

Function(s)

molecular_function
ATP binding
unfolded protein binding
G-protein coupled receptor binding
protease binding
double-stranded RNA binding
protein binding
ATPase activity
enzyme binding
heat shock protein binding
ubiquitin protein ligase binding
ATPase activity, coupled
protein binding involved in protein folding
poly(A) RNA binding
protein N-terminus binding
NF-kappaB binding