57090

• Gene Symbol: Klrk1
• Gene Name: killer cell lectin-like receptor subfamily K, member 1
• Gene Aliases: NKG2D, Nkrp2
• Chromosome Location: Chr.4: 163392652 - 163403732 on Build Rnor_6.0
• UniGene ID: Rn.14544
• Species: Rat
• Species Specific ID (Flybase ID): -

siRNA Details

Gene Symbol: Klrk1
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	NM_133512.2	NP_598196.1	6, 7	527
	XM_006237073.2	XP_006237135.1	6, 7	1709
	XM_006237074.2	XP_006237136.1	6, 7	608
	XM_006237075.2	XP_006237137.1	6, 7	677
	XM_006237076.2	XP_006237138.1	6, 7	515
	XM_006237077.2	XP_006237139.1	6, 7	565
GenBank mRNA	AF009511.1	-	5, 6	481
	FQ241294.1	-	6, 7	527

More Information

Other Species Targeted

This siRNA also targets the following transcripts in Mouse: NM_033078, NM_001083322, NM_001286018, AF039026, AK170499, and others.

Gene Ontology Categories:

Process(es)

stimulatory C-type lectin receptor signaling pathway
positive regulation of natural killer cell mediated cytotoxicity directed against tumor cell target
natural killer cell activation
cell differentiation
positive regulation of myeloid dendritic cell activation
positive regulation of interferon-gamma production
positive regulation of apoptotic process
innate immune response
positive regulation of nitric oxide biosynthetic process
positive regulation of natural killer cell mediated cytotoxicity
defense response to Gram-positive bacterium
cellular response to lipopolysaccharide

Function(s)

protein binding
kinase binding
carbohydrate binding
MHC class Ib receptor activity
MHC class I protein binding
protein homodimerization activity