59993

• Gene Symbol: Apc
• Gene Name: adenomatosis polyposis coli
• Gene Aliases: AI047805, AU020952, AW124434, CC1, Min, mAPC
• Chromosome Location: Chr.18: 34220307 - 34322190 on Build GRCm38
• UniGene ID: Mm.384171
• Species: Mouse
• Species Specific ID (Flybase ID): -

siRNA Details

Gene Symbol: Apc
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	NM_007462.3	NP_031488.2	2, 3	439
GenBank mRNA	AK042021.1	-	2, 3	440
	AK045053.1	-	2, 3	410
	AK046280.1	-	2, 3	430
	AK080907.1	-	2, 3	439
	AK082724.1	-	2, 3	185
	BC141141.1	-	1, 2	152	9055753
	M88127.1	-	1, 2	128

More Information

Other Species Targeted

This siRNA also targets the following transcripts in Human: NM_000038, NM_001127510, DA795663, DA777787, M74088, and others.

Gene Ontology Categories:

Process(es)

mitotic cytokinesis
kidney development
hair follicle development
protein complex assembly
cellular response to DNA damage stimulus
negative regulation of microtubule depolymerization
cell cycle arrest
metaphase/anaphase transition of mitotic cell cycle
mitotic spindle assembly checkpoint
establishment or maintenance of cell polarity
pattern specification process
axonogenesis
negative regulation of cell proliferation
axis specification
anterior/posterior pattern specification
dorsal/ventral pattern formation
proximal/distal pattern formation
Wnt signaling pathway
cell migration
stem cell population maintenance
negative regulation of Wnt signaling pathway
regulation of cell migration
positive regulation of cell migration
regulation of epithelial cell differentiation
positive regulation of epithelial cell differentiation
positive regulation of microtubule polymerization
cytoplasmic microtubule organization
neuron projection development
positive regulation of pseudopodium assembly
regulation of microtubule-based process
T cell differentiation in thymus
somatic stem cell population maintenance
negative regulation of odontogenesis
positive regulation of apoptotic process
negative regulation of apoptotic process
negative regulation of MAPK cascade
skin development
canonical Wnt signaling pathway involved in negative regulation of apoptotic process
canonical Wnt signaling pathway involved in positive regulation of apoptotic process
regulation of cell differentiation
positive regulation of cell differentiation
regulation of osteoblast differentiation
regulation of osteoclast differentiation
positive regulation of protein catabolic process
negative regulation of cyclin-dependent protein serine/threonine kinase activity
positive regulation of cell adhesion
muscle cell cellular homeostasis
thymus development
negative regulation of epithelial cell proliferation
regulation of nitrogen compound metabolic process
chromosome organization
regulation of cell cycle
positive regulation of cell division
regulation of attachment of spindle microtubules to kinetochore
retina development in camera-type eye
canonical Wnt signaling pathway
negative regulation of epithelial cell proliferation involved in prostate gland development
negative regulation of canonical Wnt signaling pathway
regulation of glutamate metabolic process

Function(s)

protease binding
protein binding
beta-catenin binding
microtubule binding
protein kinase regulator activity
protein kinase binding
protein complex binding
gamma-catenin binding
microtubule plus-end binding