60029

• Gene Symbol: Acvr2a
• Gene Name: activin receptor IIA
• Gene Aliases: ActrIIa, Acvr2, TactrII
• Chromosome Location: Chr.2: 48814109 - 48903264 on Build GRCm38
• UniGene ID: Mm.314338
• Species: Mouse
• Species Specific ID (Flybase ID): -

siRNA Details

Gene Symbol: Acvr2a
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	NM_007396.4	NP_031422.3	2	900
GenBank mRNA	AK041246.1	-	2	853
	AK143186.1	-	2	808
	BC138823.1	-	2	561	8861845
	M65287.1	-	2	307

More Information

Other Species Targeted

This siRNA also targets the following transcripts in Human: NM_001616, NM_001278579, NM_001278580, X63128, BC067417, and others.
This siRNA also targets the following transcripts in Rat: NM_031571, XM_008761703, S48190, L10639.

Gene Ontology Categories:

Process(es)

gastrulation with mouth forming second
positive regulation of protein phosphorylation
protein phosphorylation
transmembrane receptor protein serine/threonine kinase signaling pathway
spermatogenesis
determination of left/right symmetry
mesoderm development
male gonad development
anterior/posterior pattern specification
regulation of signal transduction
positive regulation of pathway-restricted SMAD protein phosphorylation
phosphorylation
positive regulation of bone mineralization
BMP signaling pathway
regulation of BMP signaling pathway
activin receptor signaling pathway
positive regulation of activin receptor signaling pathway
sperm ejaculation
penile erection
positive regulation of erythrocyte differentiation
positive regulation of osteoblast differentiation
positive regulation of follicle-stimulating hormone secretion
embryonic skeletal system development
regulation of nitric-oxide synthase activity
Sertoli cell proliferation
cellular response to BMP stimulus

Function(s)

nucleotide binding
protein kinase activity
protein serine/threonine kinase activity
transmembrane receptor protein serine/threonine kinase activity
receptor signaling protein serine/threonine kinase activity
protein binding
ATP binding
coreceptor activity
kinase activity
activin receptor activity, type II
transferase activity
transferase activity, transferring phosphorus-containing groups
activin-activated receptor activity
growth factor binding
PDZ domain binding
inhibin binding
protein self-association
metal ion binding
activin binding