60224

• Gene Symbol: Bad
• Gene Name: BCL2-associated agonist of cell death
• Gene Aliases: AI325008, Bbc2
• Chromosome Location: Chr.19: 6941861 - 6951905 on Build GRCm38
• UniGene ID: Mm.4387
• Species: Mouse
• Species Specific ID (Flybase ID): -

siRNA Details

Gene Symbol: Bad
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	NM_001285453.1	NP_001272382.1	3	317
	NM_007522.3	NP_031548.1	3	834
GenBank mRNA	AK131666.1	-	3	279
	AK151792.1	-	3	282
	AK169002.1	-	3	279
	BC006762.1	-	3	802	3257589
	L37296.1	-	3	842

More Information

Other Species Targeted

This siRNA also targets the following transcripts in Rat: NM_022698, XM_006230897, XM_006230898, XM_006230896, AF279910, and others.

Gene Ontology Categories:

Process(es)

release of cytochrome c from mitochondria
glucose catabolic process
apoptotic process
activation of cysteine-type endopeptidase activity involved in apoptotic process
cell proliferation
extrinsic apoptotic signaling pathway via death domain receptors
intrinsic apoptotic signaling pathway in response to DNA damage
positive regulation of mitochondrial membrane potential
suppression by virus of host apoptotic process
cytokine-mediated signaling pathway
positive regulation of insulin secretion
positive regulation of glucokinase activity
positive regulation of insulin secretion involved in cellular response to glucose stimulus
glucose homeostasis
regulation of apoptotic process
positive regulation of apoptotic process
positive regulation of cysteine-type endopeptidase activity involved in apoptotic process
regulation of cysteine-type endopeptidase activity involved in apoptotic process
type B pancreatic cell proliferation
positive regulation of B cell differentiation
positive regulation of T cell differentiation
positive regulation of proteolysis
negative regulation of cytolysis
ADP metabolic process
ATP metabolic process
regulation of mitochondrial membrane permeability
pore complex assembly
positive regulation of epithelial cell proliferation
positive regulation of apoptotic process by virus
cellular process regulating host cell cycle in response to virus
cellular response to organic substance
cellular response to nicotine
positive regulation of release of cytochrome c from mitochondria
apoptotic signaling pathway
extrinsic apoptotic signaling pathway
extrinsic apoptotic signaling pathway in absence of ligand
intrinsic apoptotic signaling pathway
activation of cysteine-type endopeptidase activity
positive regulation of neuron death
positive regulation of type B pancreatic cell development

Function(s)

protein binding
phospholipid binding
lipid binding
cysteine-type endopeptidase activator activity involved in apoptotic process
protein kinase binding
protein phosphatase binding
protein phosphatase 2B binding
protein kinase B binding
protein heterodimerization activity