61560

• Gene Symbol: Fgfr3
• Gene Name: fibroblast growth factor receptor 3
• Gene Aliases: CD333, FR3, Fgfr-3, Flg-2, HBGFR, Mfr3, sam3
• Chromosome Location: Chr.5: 33721724 - 33737068 on Build GRCm38
• UniGene ID: Mm.6904
• Species: Mouse
• Species Specific ID (Flybase ID): -

siRNA Details

Gene Symbol: Fgfr3
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	NM_001163215.2	NP_001156687.1	14	2205
	NM_001163216.2	NP_001156688.1	12	1920
	NM_001163217.2	NP_001156689.1	13	1980
	NM_001205270.1	NP_001192199.1	14	2182
	NM_008010.5	NP_032036.2	14	2179
GenBank mRNA	AF024638.1	-	12	1828
	AK143592.1	-	14	2115
	AK163495.1	-	12	1758
	BC053056.1	-	14	2089	5708838
	M81342.1	-	14	2097
	S56291.1	-	13	1924
	X58255.1	-	14	2083

More Information

Other Species Targeted

This siRNA also targets the following transcripts in Human: NM_022963, NM_213647, NM_002011, M59373, AK225909, and others.
This siRNA also targets the following transcripts in Rat: NM_053429, XM_006251396, XM_006251395, XM_006251390, XM_006251393, and others.

Gene Ontology Categories:

Process(es)

negative regulation of transcription from RNA polymerase II promoter
MAPK cascade
skeletal system development
positive regulation of endothelial cell proliferation
morphogenesis of an epithelium
lens morphogenesis in camera-type eye
protein phosphorylation
apoptotic process
cell-cell signaling
positive regulation of cell proliferation
negative regulation of cell proliferation
fibroblast growth factor receptor signaling pathway
positive regulation of phospholipase activity
oligodendrocyte development
phosphorylation
peptidyl-tyrosine phosphorylation
substantia nigra development
central nervous system myelination
cell differentiation
bone mineralization
forebrain development
positive regulation of protein ubiquitination
somatic stem cell population maintenance
post-anal tail morphogenesis
positive regulation of tyrosine phosphorylation of Stat1 protein
positive regulation of tyrosine phosphorylation of Stat3 protein
positive regulation of MAPK cascade
positive regulation of neuron apoptotic process
positive regulation of phosphatidylinositol 3-kinase activity
positive regulation of cell differentiation
negative regulation of mitotic nuclear division
negative regulation of smoothened signaling pathway
protein autophosphorylation
digestive tract morphogenesis
negative regulation of developmental growth
response to axon injury
negative regulation of astrocyte differentiation
inner ear development
negative regulation of epithelial cell proliferation
positive regulation of peptidyl-tyrosine phosphorylation
cartilage development
inner ear receptor cell differentiation
bone morphogenesis
axonogenesis involved in innervation
alveolar secondary septum development
lens fiber cell development
positive regulation of ERK1 and ERK2 cascade
bone maturation
epithelial cell fate commitment
positive regulation of MAPKKK cascade by fibroblast growth factor receptor signaling pathway
cochlea development
positive regulation of canonical Wnt signaling pathway
fibroblast growth factor receptor apoptotic signaling pathway

Function(s)

nucleotide binding
protein kinase activity
protein tyrosine kinase activity
transmembrane receptor protein tyrosine kinase activity
fibroblast growth factor-activated receptor activity
protein binding
ATP binding
kinase activity
transferase activity
transferase activity, transferring phosphorus-containing groups
fibroblast growth factor binding