61879

• Gene Symbol: Grin2b
• Gene Name: glutamate receptor, ionotropic, NMDA2B (epsilon 2)
• Gene Aliases: AW490526, GluN2B, NR2B, Nmdar2b
• Chromosome Location: Chr.6: 135715272 - 136173819 on Build GRCm38
• UniGene ID: Mm.436649
• Species: Mouse
• Species Specific ID (Flybase ID): -

siRNA Details

Gene Symbol: Grin2b
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	NM_008171.3	NP_032197.3	4, 5	1182
GenBank mRNA	AK002963.1	-	4, 5	1183
	D10651.2	-	1, 2	419

More Information

Other Species Targeted

This siRNA also targets the following transcripts in Rat: NM_012574, M91562, U11419.

Gene Ontology Categories:

Process(es)

action potential
behavioral fear response
in utero embryonic development
startle response
suckling behavior
transport
ion transport
cation transport
calcium ion transport
chemical synaptic transmission
sensory organ development
learning or memory
learning
memory
associative learning
embryo development
regulation of protein kinase A signaling
positive regulation of cell death
positive regulation of glutamate secretion
ion transmembrane transport
ionotropic glutamate receptor signaling pathway
synaptic transmission, glutamatergic
fear response
receptor clustering
regulation of MAPK cascade
response to ethanol
regulation of synaptic plasticity
regulation of neuronal synaptic plasticity
regulation of long-term neuronal synaptic plasticity
behavioral response to pain
rhythmic process
positive regulation of synaptic transmission
detection of mechanical stimulus involved in sensory perception of pain
regulation of postsynaptic membrane potential
excitatory postsynaptic potential
long-term synaptic potentiation
calcium ion transmembrane transport
cation transmembrane transport

Function(s)

receptor activity
ionotropic glutamate receptor activity
NMDA glutamate receptor activity
receptor binding
interleukin-1 receptor binding
ion channel activity
extracellular-glutamate-gated ion channel activity
cation channel activity
calcium channel activity
protein binding
beta-catenin binding
drug binding
zinc ion binding
glycine binding
D2 dopamine receptor binding
ionotropic glutamate receptor binding
neurotransmitter binding
metal ion binding
protein heterodimerization activity
cell adhesion molecule binding