62030

• Gene Symbol: Gli3
• Gene Name: GLI-Kruppel family member GLI3
• Gene Aliases: AI854843, AU023367, Bph, GLI3-190, GLI3FL, Pdn, Xt, add
• Chromosome Location: Chr.13: 15463235 - 15730026 on Build GRCm38
• UniGene ID: Mm.5098
• Species: Mouse
• Species Specific ID (Flybase ID): -

siRNA Details

Gene Symbol: Gli3
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	NM_008130.2	NP_032156.2	14	2784
GenBank mRNA	BC141135.1	-	14	2485	9055747
	BC145445.1	-	14	2485	9054003
	CA752350.1	-	3	642
	X95255.1	-	14	2524

More Information

Other Species Targeted

This siRNA also targets the following transcripts in Human: NM_000168, BC113616, AK308429, BC117168, M57609, and others.

Gene Ontology Categories:

Process(es)

negative regulation of transcription from RNA polymerase II promoter
metanephros development
branching involved in ureteric bud morphogenesis
in utero embryonic development
kidney development
positive regulation of neuroblast proliferation
transcription, DNA-templated
regulation of transcription, DNA-templated
smoothened signaling pathway
pattern specification process
axon guidance
central nervous system development
brain development
hindgut morphogenesis
heart development
negative regulation of cell proliferation
anterior/posterior pattern specification
dorsal/ventral pattern formation
proximal/distal pattern formation
regulation of gene expression
protein processing
spinal cord dorsal/ventral patterning
spinal cord motor neuron differentiation
telencephalon development
pallium development
subpallium development
optic nerve morphogenesis
hippocampus development
smoothened signaling pathway involved in ventral spinal cord interneuron specification
smoothened signaling pathway involved in spinal cord motor neuron cell fate specification
forebrain dorsal/ventral pattern formation
cerebral cortex radial glia guided migration
layer formation in cerebral cortex
forebrain radial glial cell differentiation
neural tube development
lateral ganglionic eminence cell proliferation
melanocyte differentiation
lung development
embryonic limb morphogenesis
mammary gland development
forebrain development
positive regulation of chondrocyte differentiation
T cell differentiation in thymus
limb morphogenesis
tube development
regulation of cell proliferation
positive regulation of protein import into nucleus
odontogenesis of dentin-containing tooth
embryonic digit morphogenesis
regulation of apoptotic process
camera-type eye development
negative regulation of apoptotic process
tongue development
negative thymic T cell selection
regulation of cell differentiation
negative regulation of cell differentiation
negative regulation of neuron differentiation
positive regulation of osteoblast differentiation
negative regulation of smoothened signaling pathway
negative regulation of transcription, DNA-templated
positive regulation of transcription, DNA-templated
positive regulation of transcription from RNA polymerase II promoter
positive regulation of alpha-beta T cell differentiation
negative regulation of alpha-beta T cell differentiation
embryonic digestive tract morphogenesis
embryonic digestive tract development
developmental growth
camera-type eye morphogenesis
embryonic morphogenesis
anatomical structure formation involved in morphogenesis
neuron fate commitment
embryonic skeletal system morphogenesis
oligodendrocyte differentiation
branching morphogenesis of an epithelial tube
inner ear development
anatomical structure development
palate development
limb development
frontal suture morphogenesis
lambdoid suture morphogenesis
sagittal suture morphogenesis
mammary gland specification
smoothened signaling pathway involved in dorsal/ventral neural tube patterning
artery development
anterior semicircular canal development
lateral semicircular canal development
cell differentiation involved in kidney development
thymocyte apoptotic process
negative regulation of canonical Wnt signaling pathway

Function(s)

RNA polymerase II core promoter proximal region sequence-specific DNA binding
nucleic acid binding
DNA binding
chromatin binding
transcription factor activity, sequence-specific DNA binding
protein binding
beta-catenin binding
histone acetyltransferase binding
histone deacetylase binding
sequence-specific DNA binding
metal ion binding