63882

• Gene Symbol: Map2k1
• Gene Name: mitogen-activated protein kinase kinase 1
• Gene Aliases: MAPKK1, MEKK1, Mek1, Prkmk1
• Chromosome Location: Chr.9: 64185770 - 64253605 on Build GRCm38
• UniGene ID: Mm.248907
• Species: Mouse
• Species Specific ID (Flybase ID): -

siRNA Details

Gene Symbol: Map2k1
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	NM_008927.3	NP_032953.1	2	573
GenBank mRNA	AB041567.1	-	2	553
	AK146233.1	-	2	563
	AK146931.1	-	2	566
	AK154793.1	-	2	600
	AK165664.1	-	1	107
	AK165894.1	-	2	574
	AK167336.1	-	2	540
	BC051137.1	-	2	392
	BC054754.1	-	2	352	6411664
	L02526.1	-	2	300

More Information

Other Species Targeted

This siRNA also targets the following transcripts in Rat: NM_031643, AI603089, BC089772, D13341, Z16415, and others.

Gene Ontology Categories:

Process(es)

MAPK cascade
activation of MAPK activity
regulation of protein phosphorylation
regulation of vascular smooth muscle contraction
protein phosphorylation
response to oxidative stress
cell cycle arrest
mitotic nuclear division
cell proliferation
negative regulation of cell proliferation
positive regulation of gene expression
phosphorylation
neuron differentiation
keratinocyte differentiation
positive regulation of cell migration
melanosome transport
regulation of stress-activated MAPK cascade
positive regulation of transcription elongation from RNA polymerase II promoter
negative regulation of homotypic cell-cell adhesion
peptidyl-tyrosine dephosphorylation
positive regulation of GTPase activity
positive regulation of cell differentiation
positive regulation of Ras protein signal transduction
vesicle transport along microtubule
Golgi inheritance
response to axon injury
regulation of axon regeneration
neuron projection morphogenesis
cell motility
positive regulation of axonogenesis
protein heterooligomerization
response to glucocorticoid
lung morphogenesis
trachea formation
epithelial cell proliferation involved in lung morphogenesis
placenta blood vessel development
labyrinthine layer development
ERK1 and ERK2 cascade
positive regulation of protein serine/threonine kinase activity
regulation of Golgi inheritance
cellular senescence
mitophagy in response to mitochondrial depolarization
regulation of early endosome to late endosome transport

Function(s)

nucleotide binding
protein kinase activity
protein serine/threonine kinase activity
MAP kinase kinase activity
protein serine/threonine/tyrosine kinase activity
protein tyrosine kinase activity
receptor signaling protein tyrosine phosphatase activity
protein binding
ATP binding
protein C-terminus binding
kinase activity
transferase activity
transferase activity, transferring phosphorus-containing groups
Ras GTPase binding
protein kinase binding
mitogen-activated protein kinase kinase kinase binding
protein serine/threonine kinase activator activity
protein N-terminus binding