64894

• Gene Symbol: Tgfbr2
• Gene Name: transforming growth factor, beta receptor II
• Gene Aliases: 1110020H15Rik, AU042018, DNIIR, RIIDN, TBR-II, TbetaR-II, TbetaRII
• Chromosome Location: Chr.9: 116087695 - 116175363 on Build GRCm38
• UniGene ID: Mm.172346
• Species: Mouse
• Species Specific ID (Flybase ID): -

siRNA Details

Gene Symbol: Tgfbr2
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	NM_009371.3	NP_033397.3	3, 4	675
	NM_029575.3	NP_083851.3	2, 3	600
GenBank mRNA	AF406755.1	-	2, 3	274
	AK043619.1	-	3, 4	759
	AK046561.1	-	3, 4	601
	AK053793.1	-	3, 4	676
	AK148167.1	-	2, 3	600
	AK159327.1	-	3, 4	655
	BC052629.1	-		577

More Information

Other Species Targeted

This siRNA also targets the following transcripts in Rat: NM_031132, XM_008766690, L09653, S67770, GU067683.

Gene Ontology Categories:

Process(es)

patterning of blood vessels
vasculogenesis
in utero embryonic development
positive regulation of mesenchymal cell proliferation
lens development in camera-type eye
positive regulation of tolerance induction to self antigen
positive regulation of B cell tolerance induction
positive regulation of T cell tolerance induction
growth plate cartilage development
growth plate cartilage chondrocyte growth
protein phosphorylation
receptor-mediated endocytosis
apoptotic process
transmembrane receptor protein serine/threonine kinase signaling pathway
transforming growth factor beta receptor signaling pathway
common-partner SMAD protein phosphorylation
Notch signaling pathway
smoothened signaling pathway
gastrulation
brain development
heart development
negative regulation of cell proliferation
organ morphogenesis
regulation of gene expression
positive regulation of epithelial cell migration
phosphorylation
peptidyl-serine phosphorylation
peptidyl-threonine phosphorylation
cell differentiation
lung development
activation of protein kinase activity
embryonic hemopoiesis
regulation of growth
regulation of cell proliferation
response to drug
myeloid dendritic cell differentiation
positive regulation of angiogenesis
positive regulation of smooth muscle cell proliferation
embryonic cranial skeleton morphogenesis
positive regulation of NK T cell differentiation
cartilage development
palate development
negative regulation of cardiac muscle cell proliferation
pathway-restricted SMAD protein phosphorylation
lung morphogenesis
bronchus development
bronchus morphogenesis
trachea morphogenesis
trachea formation
mammary gland morphogenesis
lung lobe morphogenesis
response to cholesterol
lens fiber cell apoptotic process
positive regulation of reactive oxygen species metabolic process

Function(s)

nucleotide binding
protein kinase activity
protein serine/threonine kinase activity
transmembrane receptor protein serine/threonine kinase activity
receptor signaling protein serine/threonine kinase activity
receptor activity
transforming growth factor beta-activated receptor activity
transforming growth factor beta receptor activity, type II
protein binding
ATP binding
glycosaminoglycan binding
kinase activity
transferase activity
transferase activity, transferring phosphorus-containing groups
mitogen-activated protein kinase kinase kinase binding
type I transforming growth factor beta receptor binding
type III transforming growth factor beta receptor binding
SMAD binding
metal ion binding
transforming growth factor beta binding