65067

• Gene Symbol: Tert
• Gene Name: telomerase reverse transcriptase
• Gene Aliases: EST2, TCS1, TP2, TR, TRT
• Chromosome Location: Chr.13: 73626797 - 73649843 on Build GRCm38
• UniGene ID: Mm.10109
• Species: Mouse
• Species Specific ID (Flybase ID): -

siRNA Details

Gene Symbol: Tert
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	NM_009354.1	NP_033380.1	5, 6	2121
GenBank mRNA	AF051911.1	-	5, 6	2121
	AF073311.1	-	5, 6	2092
	BC082327.1	-	6, 7	1623
	BC127068.1	-	6, 7	1409	40110173
	FJ154427.1	-	1, 2	14

More Information

Other Species Targeted

This siRNA also targets the following transcripts in Rat: NM_053423, XM_008758683, XM_008758684, AY539720, AY539718, and others.

Gene Ontology Categories:

Process(es)

transcription, RNA-templated
RNA-dependent DNA biosynthetic process
telomere maintenance via telomerase
mitochondrion organization
negative regulation of gene expression
DNA strand elongation
positive regulation of Wnt signaling pathway
production of siRNA involved in RNA interference
RNA biosynthetic process
positive regulation of hair cycle
positive regulation of nitric-oxide synthase activity
cellular response to hypoxia
DNA biosynthetic process
replicative senescence
positive regulation of pri-miRNA transcription from RNA polymerase II promoter
negative regulation of production of siRNA involved in RNA interference
positive regulation of stem cell proliferation
negative regulation of cellular senescence
negative regulation of extrinsic apoptotic signaling pathway in absence of ligand

Function(s)

tRNA binding
transcription coactivator binding
DNA binding
telomerase activity
telomerase RNA reverse transcriptase activity
RNA binding
RNA-directed DNA polymerase activity
RNA-directed RNA polymerase activity
protein binding
transferase activity
nucleotidyltransferase activity
telomeric DNA binding
protein homodimerization activity
metal ion binding
telomerase RNA binding