65177

• Gene Symbol: Nr1h2
• Gene Name: nuclear receptor subfamily 1, group H, member 2
• Gene Aliases: AI194859, LXR, LXRB, LXRbeta, NER1, OR-1, RIP15, UR, Unr, Unr2
• Chromosome Location: Chr.7: 44549616 - 44553969 on Build GRCm38
• UniGene ID: Mm.968
• Species: Mouse
• Species Specific ID (Flybase ID): -

siRNA Details

Gene Symbol: Nr1h2
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	NM_001285517.1	NP_001272446.1	6	772
	NM_001285518.1	NP_001272447.1	6	766
	NM_001285519.1	NP_001272448.1	6	763
	NM_009473.3	NP_033499.1	6	779
GenBank mRNA	AK054508.1	-	6	750
	AK077620.1	-	6	745
	AK134489.1	-	6	728
	AK156777.1	-	6	747
	BC066025.1	-	6	730	6829527
	BC106148.1	-	5	499
	BQ573162.1	-	6	749
	EU869275.2	-	3	758
	U09419.1	-	5	597

More Information

Other Species Targeted

This siRNA also targets the following transcripts in Rat: NM_031626, U20389, BC157812, U14533.

Gene Ontology Categories:

Process(es)

negative regulation of transcription from RNA polymerase II promoter
transcription, DNA-templated
regulation of transcription, DNA-templated
regulation of transcription from RNA polymerase II promoter
transcription from RNA polymerase II promoter
positive regulation of gene expression
negative regulation of gene expression
positive regulation of triglyceride biosynthetic process
positive regulation of cholesterol efflux
positive regulation of lipid storage
negative regulation of cholesterol storage
intracellular receptor signaling pathway
positive regulation of cellular protein metabolic process
negative regulation of lipid transport
positive regulation of cholesterol transport
cholesterol homeostasis
steroid hormone mediated signaling pathway
cellular lipid metabolic process
positive regulation of fatty acid biosynthetic process
negative regulation of proteolysis
negative regulation of transcription, DNA-templated
positive regulation of transcription from RNA polymerase II promoter
retinoic acid receptor signaling pathway
negative regulation of pinocytosis
positive regulation of lipoprotein lipase activity
lipid homeostasis
positive regulation of high-density lipoprotein particle assembly
positive regulation of pancreatic juice secretion
positive regulation of secretion of lysosomal enzymes
regulation of cholesterol homeostasis

Function(s)

RNA polymerase II core promoter proximal region sequence-specific DNA binding
transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding
RNA polymerase II transcription factor activity, sequence-specific transcription regulatory region DNA binding
DNA binding
transcription factor activity, sequence-specific DNA binding
steroid hormone receptor activity
RNA polymerase II transcription factor activity, ligand-activated sequence-specific DNA binding
protein binding
zinc ion binding
apolipoprotein A-I receptor binding
sequence-specific DNA binding
metal ion binding
retinoid X receptor binding
ATPase binding