6560

• Gene Symbol: ABCB4
• Gene Name: ATP binding cassette subfamily B member 4
• Gene Aliases: ABC21, GBD1, ICP3, MDR2, MDR2/3, MDR3, PFIC-3, PGY3
• Chromosome Location: Chr.7: 87399461 - 87475864 on Build GRCh38
• UniGene ID: Hs.654403
• Species: Human
• Species Specific ID (Flybase ID): -

siRNA Details

Gene Symbol: ABCB4
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	NM_000443.3	NP_000434.1	4	240
	NM_018849.2	NP_061337.1	4	240
	NM_018850.2	NP_061338.1	4	240
	XM_011516308.2	XP_011514610.2	4	264
	XM_011516309.2	XP_011514611.2	4	264
	XM_011516310.2	XP_011514612.2	4	264
	XM_011516311.2	XP_011514613.2	4	264
	XM_011516312.2	XP_011514614.2	4	264
	XM_011516313.2	XP_011514615.1	4	263
	XM_017012323.1	XP_016867812.1	4	251
GenBank mRNA	BC020618.2	-	3	171
	BC042531.1	-	4	276	4837724
	M23234.1	-	4	196
	Z35284.1	-	7	2013

More Information

Gene Ontology Categories:

Process(es)

antigen processing and presentation of exogenous protein antigen via MHC class Ib, TAP-dependent
antigen processing and presentation of endogenous peptide antigen via MHC class I via ER pathway, TAP-dependent
antigen processing and presentation of endogenous peptide antigen via MHC class Ib via ER pathway, TAP-dependent
positive regulation of antigen processing and presentation of peptide antigen via MHC class I
lipid metabolic process
transport
drug transmembrane transport
positive regulation of cholesterol transport
bile acid secretion
response to drug
xenobiotic transport
phospholipid translocation
transmembrane transport
lipid homeostasis
positive regulation of phospholipid translocation
response to fenofibrate
cellular response to bile acid
positive regulation of phospholipid transport

Function(s)

protein binding
ATP binding
phospholipid transporter activity
phosphatidylcholine transporter activity
xenobiotic-transporting ATPase activity
ATPase activity, coupled to transmembrane movement of substances
phosphatidylcholine-translocating ATPase activity