65745

Gene Symbol:

Rab27a Bcl2l1

Gene Name:

RAB27A, member RAS oncogene family

BCL2-like 1

Gene Aliases:

2210402C08Rik, 2410003M20Rik, 4933437C11Rik, ash

Bcl(X)L, Bcl-XL, Bcl2l, BclX, bcl-x, bcl2-L-1

Chromosome Location:

Chr.9: 73044810 - 73097623 on Build GRCm38

Chromosome Location:

Chr.2: 152758732 - 152832581 on Build GRCm38

UniGene ID:

Mm.34867

Mm.238213

Species:

Mouse

Species Specific ID (Flybase ID):

-

-

siRNA Details

Gene Symbol: Rab27a
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	NM_001301230.1	NP_001288159.1	7	2684
	NM_001301232.1	NP_001288161.1	6	2577
	NM_023635.6	NP_076124.1	6	2535
GenBank mRNA	AK008798.1	-	1	707
	AK030529.1	-	6	2481

Gene Symbol: Bcl2l1
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	NM_001289716.1	NP_001276645.1	2	728
	NM_001289717.1	NP_001276646.1	2	573
	NM_001289739.1	NP_001276668.1	2	728
	NM_009743.5	NP_033873.3	2	522
GenBank mRNA	AK146461.1	-	2	678
	AK150028.1	-	2	465
	AK172250.1	-	2	489
	BC089016.1	-	2	476	30606568
	BC089017.1	-	1	313	30605282
	L35049.1	-	2	526
	U10100.1	-	1	284
	U10101.1	-	1	284
	U10102.1	-	2	521
	U51277.1	-	2	661
	U51278.1	-	1	386
	U51279.1	-	2	519
	X83574.1	-	1	284

More Information

Additional Information:

This siRNA no longer meets our design criteria. We suggest you choose a different siRNA for this gene or contact Tech Support for more information.

Gene Ontology Categories:

Process(es)

protein targeting
exocytosis
vesicle docking involved in exocytosis
small GTPase mediated signal transduction
blood coagulation
protein secretion
positive regulation of gene expression
protein transport
vesicle-mediated transport
antigen processing and presentation
melanocyte differentiation
melanosome localization
melanosome transport
Rab protein signal transduction
multivesicular body organization
cytotoxic T cell degranulation
natural killer cell degranulation
pigmentation
positive regulation of exocytosis
positive regulation of phagocytosis
pigment granule localization
pigment granule transport
multivesicular body sorting pathway
complement-dependent cytotoxicity
positive regulation of regulated secretory pathway
positive regulation of reactive oxygen species biosynthetic process
positive regulation of constitutive secretory pathway
exosomal secretion
cytokinesis
ovarian follicle development
in utero embryonic development
release of cytochrome c from mitochondria
response to ischemia
apoptotic process
mitotic cell cycle checkpoint
germ cell development
spermatogenesis
cell proliferation
positive regulation of cell proliferation
male gonad development
intrinsic apoptotic signaling pathway in response to DNA damage
response to radiation
fertilization
response to virus
suppression by virus of host apoptotic process
response to cytokine
growth
regulation of apoptotic process
positive regulation of apoptotic process
negative regulation of apoptotic process
negative regulation of cysteine-type endopeptidase activity involved in apoptotic process
negative regulation of neuron apoptotic process
response to cycloheximide
regulation of mitochondrial membrane permeability
neuron apoptotic process
regulation of mitochondrial membrane potential
cellular process regulating host cell cycle in response to virus
mitochondrion morphogenesis
cellular response to amino acid stimulus
cellular response to alkaloid
cellular response to gamma radiation
apoptotic process in bone marrow
negative regulation of establishment of protein localization to plasma membrane
negative regulation of release of cytochrome c from mitochondria
extrinsic apoptotic signaling pathway in absence of ligand
hepatocyte apoptotic process
negative regulation of execution phase of apoptosis
negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage
negative regulation of anoikis
negative regulation of intrinsic apoptotic signaling pathway

Function(s)

nucleotide binding
GTPase activity
protein binding
GTP binding
GDP binding
protein domain specific binding
myosin V binding
protein kinase binding
identical protein binding
protein homodimerization activity
cysteine-type endopeptidase inhibitor activity involved in apoptotic process
protein heterodimerization activity
BH domain binding
BH3 domain binding
MDM2/MDM4 family protein binding