66919

• Gene Symbol: Fgfr2
• Gene Name: fibroblast growth factor receptor 2
• Gene Aliases: AU043015, AW556123, Bek, Fgfr-2, Fgfr-7, Fgfr7, KGFR, KGFRTr, svs
• Chromosome Location: Chr.7: 130162451 - 130266944 on Build GRCm38
• UniGene ID: Mm.16340
• Species: Mouse
• Species Specific ID (Flybase ID): -

siRNA Details

Gene Symbol: Fgfr2
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	NM_010207.2	NP_034337.2	3	1518
GenBank mRNA	AK038588.1	-	3	935
	BC072640.1	-	3	955
	EF143323.1	-	2	294
	EF143328.1	-	2	294
	EF143329.1	-	2	294
	EF143335.1	-	2	294
	EF143338.1	-	2	294
	M86441.1	-	3	900
	X55441.1	-	3	951

More Information

Other Species Targeted

This siRNA also targets the following transcripts in Rat: NM_001109892, NM_012712, XM_006230392, XM_006230389, XM_006230390, and others.

Gene Ontology Categories:

Process(es)

negative regulation of transcription from RNA polymerase II promoter
angiogenesis
ureteric bud development
in utero embryonic development
epithelial to mesenchymal transition
positive regulation of mesenchymal cell proliferation
outflow tract septum morphogenesis
membranous septum morphogenesis
protein phosphorylation
apoptotic process
cell-cell signaling
axonogenesis
neuromuscular junction development
positive regulation of cell proliferation
negative regulation of cell proliferation
fibroblast growth factor receptor signaling pathway
regulation of smoothened signaling pathway
post-embryonic development
embryonic pattern specification
organ morphogenesis
regulation of cell fate commitment
positive regulation of phospholipase activity
phosphorylation
morphogenesis of embryonic epithelium
peptidyl-tyrosine phosphorylation
orbitofrontal cortex development
ventricular zone neuroblast division
pyramidal neuron development
gland morphogenesis
positive regulation of Wnt signaling pathway
bone mineralization
lung development
epithelial cell differentiation
midbrain development
otic vesicle formation
hair follicle morphogenesis
lacrimal gland development
multicellular organism growth
organ growth
fibroblast growth factor receptor signaling pathway involved in negative regulation of apoptotic process in bone marrow
fibroblast growth factor receptor signaling pathway involved in hemopoiesis
fibroblast growth factor receptor signaling pathway involved in positive regulation of cell proliferation in bone marrow
fibroblast growth factor receptor signaling pathway involved in orbitofrontal cortex development
regulation of multicellular organism growth
regulation of fibroblast growth factor receptor signaling pathway
regulation of cell proliferation
inner ear morphogenesis
odontogenesis
positive regulation of MAPK cascade
cell fate commitment
positive regulation of cell cycle
negative regulation of mitotic nuclear division
positive regulation of transcription from RNA polymerase II promoter
protein autophosphorylation
lung alveolus development
synaptic vesicle transport
embryonic digestive tract morphogenesis
embryonic organ morphogenesis
digestive tract development
embryonic organ development
reproductive structure development
positive regulation of smooth muscle cell proliferation
embryonic cranial skeleton morphogenesis
epidermis morphogenesis
branching morphogenesis of a nerve
mesenchymal cell differentiation
epithelial cell proliferation
regulation of epithelial cell proliferation
positive regulation of epithelial cell proliferation
negative regulation of epithelial cell proliferation
regulation of smooth muscle cell differentiation
positive regulation of cell division
ventricular cardiac muscle tissue morphogenesis
positive regulation of cardiac muscle cell proliferation
limb bud formation
bone development
bone morphogenesis
coronal suture morphogenesis
epithelial tube branching involved in lung morphogenesis
branching involved in prostate gland morphogenesis
branching involved in salivary gland morphogenesis
bud elongation involved in lung branching
lung lobe morphogenesis
lung-associated mesenchyme development
positive regulation of epithelial cell proliferation involved in lung morphogenesis
prostate gland morphogenesis
prostate epithelial cord elongation
prostate epithelial cord arborization involved in prostate glandular acinus morphogenesis
squamous basal epithelial stem cell differentiation involved in prostate gland acinus development
fibroblast growth factor receptor signaling pathway involved in mammary gland specification
lateral sprouting from an epithelium
mammary gland bud formation
epithelial cell proliferation involved in salivary gland morphogenesis
branch elongation involved in salivary gland morphogenesis
branching involved in labyrinthine layer morphogenesis
regulation of branching involved in prostate gland morphogenesis
regulation of morphogenesis of a branching structure
mesenchymal cell differentiation involved in lung development
mesenchymal cell proliferation involved in lung development
vasculogenesis involved in coronary vascular morphogenesis
endodermal digestive tract morphogenesis
lens fiber cell development
regulation of ERK1 and ERK2 cascade
positive regulation of ERK1 and ERK2 cascade
positive regulation of canonical Wnt signaling pathway

Function(s)

nucleotide binding
protein kinase activity
protein tyrosine kinase activity
transmembrane receptor protein tyrosine kinase activity
fibroblast growth factor-activated receptor activity
protein binding
ATP binding
heparin binding
kinase activity
transferase activity
transferase activity, transferring phosphorus-containing groups
fibroblast growth factor binding
protein homodimerization activity