69074

• Gene Symbol: Ccl2
• Gene Name: chemokine (C-C motif) ligand 2
• Gene Aliases: AI323594, HC11, JE, MCAF, MCP-1, MCP1, SMC-CF, Scya2, Sigje
• Chromosome Location: Chr.11: 82035577 - 82037452 on Build GRCm38
• UniGene ID: Mm.290320
• Species: Mouse
• Species Specific ID (Flybase ID): -

siRNA Details

Gene Symbol: Ccl2
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	NM_011333.3	NP_035463.1	2	266
GenBank mRNA	AF065929.1	-	2	204
	AF065930.1	-	2	204
	AF065931.1	-	2	204
	AF065932.1	-	2	204
	AF065933.1	-	2	204
	AK132590.1	-	2	265
	AK150937.1	-	2	267
	AK151789.1	-	2	265
	AK153443.1	-	2	265
	AK153468.1	-	2	267
	AK153520.1	-	2	267
	BC055070.1	-	2	244
	BC145867.1	-	2	233	40131170
	BC145869.1	-	2	233	40131172
	CT010187.1	-	2	181

More Information

Other Species Targeted

This siRNA also targets the following transcripts in Rat: NM_031530, AF058786, M57441.

Gene Ontology Categories:

Process(es)

angiogenesis
positive regulation of leukocyte mediated cytotoxicity
positive regulation of endothelial cell proliferation
leukocyte migration involved in inflammatory response
positive regulation of leukocyte migration
positive regulation of cellular extravasation
cellular calcium ion homeostasis
chemotaxis
inflammatory response
immune response
cytoskeleton organization
transforming growth factor beta receptor signaling pathway
glial cell migration
regulation of cell shape
response to heat
response to wounding
regulation of vascular endothelial growth factor production
positive regulation of macrophage chemotaxis
negative regulation of angiogenesis
cytokine-mediated signaling pathway
positive regulation of cell-cell adhesion
neutrophil chemotaxis
positive regulation of tumor necrosis factor production
positive regulation of collagen biosynthetic process
helper T cell extravasation
monocyte homeostasis
positive regulation of cell adhesion
vascular endothelial growth factor receptor signaling pathway
eosinophil chemotaxis
macrophage chemotaxis
lymphocyte chemotaxis
positive regulation of synaptic transmission
positive regulation of T cell activation
positive regulation of nitric-oxide synthase biosynthetic process
chemokine-mediated signaling pathway
cellular response to lipopolysaccharide
cellular response to interferon-gamma
cellular response to interleukin-1
cellular response to tumor necrosis factor
positive regulation of monocyte chemotaxis
positive regulation of immune complex clearance by monocytes and macrophages
positive regulation of protein targeting to membrane
positive regulation of apoptotic cell clearance

Function(s)

G-protein coupled receptor binding
cytokine activity
protein binding
chemokine activity
heparin binding
CCR2 chemokine receptor binding