69665

• Gene Symbol: Tsc2
• Gene Name: tuberous sclerosis 2
• Gene Aliases: Nafld, Tcs2
• Chromosome Location: Chr.17: 24595816 - 24632627 on Build GRCm38
• UniGene ID: Mm.30435
• Species: Mouse
• Species Specific ID (Flybase ID): -

siRNA Details

Gene Symbol: Tsc2
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	NM_001039363.2	NP_001034452.1	2	213
	NM_001286713.1	NP_001273642.1	2	213
	NM_001286714.1	NP_001273643.1	2	208
	NM_001286716.1	NP_001273645.1	2	208
	NM_001286718.1	NP_001273647.1	2	213
	NM_001286720.1	NP_001273649.1	2	213
	NM_011647.3	NP_035777.2	2	213
GenBank mRNA	AK143799.1	-	2	214
	AK147016.1	-	2	189
	AK147302.1	-	2	153
	AK147487.1	-	2	182
	AK147874.1	-	2	178
	AK147908.1	-	2	214
	AK148062.1	-	2	205
	AK170589.1	-	2	204
	AK171007.1	-	2	185
	AK196271.1	-	1	68
	BC052449.1	-	2	189	6409037
	BC060701.1	-	2	189	6409037
	BY742714.1	-	2	217
	U37775.1	-	1	128
	U39818.1	-	2	184

More Information

Gene Ontology Categories:

Process(es)

response to hypoxia
neural tube closure
negative regulation of protein kinase activity
protein import into nucleus
signal transduction
heart development
protein localization
negative regulation of cell proliferation
phosphatidylinositol 3-kinase signaling
negative regulation of phosphatidylinositol 3-kinase signaling
cell projection organization
regulation of endocytosis
negative regulation of Wnt signaling pathway
negative regulation of TOR signaling
cellular response to insulin stimulus
negative regulation of MAP kinase activity
protein kinase B signaling
positive regulation of GTPase activity
protein transport into plasma membrane raft
establishment of protein localization
negative regulation of cell size
positive regulation of transcription from RNA polymerase II promoter
glucose import
regulation of insulin receptor signaling pathway
negative regulation of insulin receptor signaling pathway
insulin-like growth factor receptor signaling pathway
negative regulation of epithelial cell proliferation
positive chemotaxis
regulation of small GTPase mediated signal transduction
protein homooligomerization
protein heterooligomerization
regulation of cell cycle
negative regulation of protein kinase B signaling

Function(s)

GTPase activator activity
protein binding
phosphatase binding
protein homodimerization activity
protein heterodimerization activity
14-3-3 protein binding