7830

• Gene Symbol: FBN1
• Gene Name: fibrillin 1
• Gene Aliases: ACMICD, ECTOL1, FBN, GPHYSD2, MASS, MFLS, MFS1, OCTD, SGS, SSKS, WMS, WMS2
• Chromosome Location: Chr.15: 48408306 - 48645788 on Build GRCh38
• UniGene ID: Hs.591133
• Species: Human
• Species Specific ID (Flybase ID): -

siRNA Details

Gene Symbol: FBN1
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	NM_000138.4	NP_000129.3	2, 3	566
GenBank mRNA	AK304737.1	-	2, 3	487
	BC146854.1	-	2, 3	432	9056782
	L13923.1	-	1, 2	304
	X63556.1	-	2, 3	566

More Information

Other Species Targeted

This siRNA also targets the following transcripts in Rat: NM_031825, XM_008762203, XM_006234935, XM_008762202, AF135059.
This siRNA also targets the following transcripts in Mouse: NM_007993, U19972, L29454, AK046621, U22493, and others.

Gene Ontology Categories:

Process(es)

skeletal system development
metanephros development
heart development
extracellular matrix disassembly
extracellular matrix organization
sequestering of BMP in extracellular matrix
sequestering of TGFbeta in extracellular matrix
camera-type eye development
embryonic eye morphogenesis
post-embryonic eye morphogenesis
cellular response to transforming growth factor beta stimulus
regulation of cellular response to growth factor stimulus
cellular response to insulin-like growth factor stimulus

Function(s)

integrin binding
hormone activity
extracellular matrix structural constituent
calcium ion binding
protein binding
extracellular matrix constituent conferring elasticity
protein complex binding