88493

• Gene Symbol: Wt1
• Gene Name: Wilms tumor 1 homolog
• Gene Aliases: D630046I19Rik, Wt-1
• Chromosome Location: Chr.2: 105126529 - 105173614 on Build GRCm38
• UniGene ID: Mm.389339
• Species: Mouse
• Species Specific ID (Flybase ID): -

siRNA Details

Gene Symbol: Wt1
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	NM_144783.2	NP_659032.3	1, 2	922
GenBank mRNA	M55512.1	-	1, 2	927

More Information

Other Species Targeted

This siRNA also targets the following transcripts in Rat: NM_031534, XM_006234621, XM_006234620, XM_006234622, X69716.

Gene Ontology Categories:

Process(es)

negative regulation of transcription from RNA polymerase II promoter
vasculogenesis
metanephros development
ureteric bud development
branching involved in ureteric bud morphogenesis
kidney development
mesonephros development
regulation of organ formation
transcription, DNA-templated
regulation of transcription, DNA-templated
regulation of transcription from RNA polymerase II promoter
transcription from RNA polymerase II promoter
apoptotic process
germ cell development
spermatogenesis
single fertilization
thorax and anterior abdomen determination
heart development
sex determination
negative regulation of cell proliferation
RNA splicing
gonad development
male gonad development
tissue development
regulation of gene expression
negative regulation of translation
negative regulation of cell growth
sperm motility
adrenal gland development
male genitalia development
epithelial cell differentiation
glomerulus development
glomerular basement membrane development
adrenal cortex formation
camera-type eye development
positive regulation of apoptotic process
negative regulation of apoptotic process
negative regulation of transcription, DNA-templated
positive regulation of transcription, DNA-templated
positive regulation of transcription from RNA polymerase II promoter
Sertoli cell development
mesenchymal to epithelial transition
positive regulation of heart growth
diaphragm development
cardiac muscle cell fate commitment
coronary vasculature development
visceral serous pericardium development
cellular response to cAMP
cellular response to gonadotropin stimulus
metanephric mesenchyme development
glomerular visceral epithelial cell differentiation
posterior mesonephric tubule development
metanephric S-shaped body morphogenesis
negative regulation of metanephric glomerular mesangial cell proliferation
seminiferous tubule development
negative regulation of mesenchymal cell apoptotic process involved in metanephros development
positive regulation of male gonad development
negative regulation of female gonad development
positive regulation of metanephric ureteric bud development

Function(s)

transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding
nucleic acid binding
DNA binding
double-stranded DNA binding
transcription factor activity, sequence-specific DNA binding
RNA binding
protein binding
zinc ion binding
sequence-specific DNA binding
transcription regulatory region DNA binding
metal ion binding
C2H2 zinc finger domain binding