8959

• Gene Symbol: SOD2
• Gene Name: superoxide dismutase 2, mitochondrial
• Gene Aliases: IPO-B, IPOB, MNSOD, MVCD6, Mn-SOD
• Chromosome Location: Chr.6: 159679064 - 159762529 on Build GRCh38
• UniGene ID: Hs.487046
• Species: Human
• Species Specific ID (Flybase ID): -

siRNA Details

Gene Symbol: SOD2
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	NM_000636.3	NP_000627.2	4, 5	683
	NM_001024465.2	NP_001019636.1	4, 5	683
	NM_001024466.2	NP_001019637.1	3, 4	566
	NM_001322814.1	NP_001309743.1	3, 4	566
	NM_001322817.1	NP_001309746.1	6, 7	2212
	NM_001322819.1	NP_001309748.1	4, 5	589
	NM_001322820.1	NP_001309749.1	4, 5	592
GenBank mRNA	AK097395.1	-	6, 7	2209
	AK296809.1	-	3, 4	479
	AK313082.1	-	4, 5	548
	AY280718.1	-	4, 5	519
	AY280719.1	-	3, 4	511
	AY280720.1	-	3, 4	510
	AY280721.1	-	3, 4	510
	BC012423.1	-	4, 5	579	3880111
	BC035422.1	-	4, 5	579
	BM724413.1	-	3, 4	466
	BT006967.1	-	4, 5	522
	M36693.1	-	4, 5	616
	X07834.1	-	4, 5	526
	X14322.1	-	4, 5	617
	X15132.1	-	4, 5	582
	X59445.1	-	4, 5	582
	Y00472.1	-	4, 5	588
	Y00985.1	-	4, 5	616

More Information

Other Species Targeted

This siRNA also targets the following transcripts in Mouse: NM_013671, CT010273, AK167521, BC018173, AK168591, and others.

Gene Ontology Categories:

Process(es)

response to reactive oxygen species
response to superoxide
age-dependent response to reactive oxygen species
release of cytochrome c from mitochondria
vasodilation by acetylcholine involved in regulation of systemic arterial blood pressure
regulation of transcription from RNA polymerase II promoter
superoxide metabolic process
regulation of blood pressure
negative regulation of cell proliferation
removal of superoxide radicals
oxygen homeostasis
negative regulation of neuron apoptotic process
protein homotetramerization
oxidation-reduction process
negative regulation of oxidative stress-induced intrinsic apoptotic signaling pathway

Function(s)

superoxide dismutase activity
manganese ion binding
identical protein binding