9157

• Gene Symbol: PRLR
• Gene Name: prolactin receptor
• Gene Aliases: HPRL, MFAB, hPRLrI
• Chromosome Location: Chr.5: 35048295 - 35230589 on Build GRCh38
• UniGene ID: Hs.368587
• Species: Human
• Species Specific ID (Flybase ID): -

siRNA Details

Gene Symbol: PRLR
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	NM_000949.6	NP_000940.1	4	558
	NM_001204315.1	NP_001191244.1	3	236
	NM_001204316.1	NP_001191245.1	3	236
	NM_001204317.1	NP_001191246.1	3	236
	NM_001204318.1	NP_001191247.1	3	236
	XM_006714484.2	XP_006714547.1	4	376
	XM_011514068.2	XP_011512370.1	4	391
	XM_011514069.2	XP_011512371.1	4	330
	XM_017009646.1	XP_016865135.1	2	174
GenBank mRNA	AF166329.1	-	2	131
	AF416618.1	-	2	148
	AF416619.1	-	2	148
	AF492470.1	-	2	148
	AK313270.1	-	4	446
	BC059392.1	-	4	444	30343995
	DA640476.1	-	4	391
	GU133399.1	-	2	148
	KJ651922.1	-	5	560
	KJ651923.1	-	5	508
	KJ651924.1	-	4	417
	KJ651925.1	-	4	424
	M31661.1	-	4	415
	S78505.1	-	1	59

More Information

Other Species Targeted

This siRNA also targets the following transcripts in Rat: NM_012630, NM_001034111, XM_008760751, M57668, U07567, and others.
This siRNA also targets the following transcripts in Mouse: NM_011169, NM_001253782, NM_001253781, AK081676, D10214, and others.

Gene Ontology Categories:

Process(es)

steroid biosynthetic process
cell surface receptor signaling pathway
activation of transmembrane receptor protein tyrosine kinase activity
embryo implantation
lactation
regulation of cell adhesion
regulation of epithelial cell differentiation
prolactin signaling pathway
T cell activation
activation of JAK2 kinase activity
negative regulation of apoptotic process
JAK-STAT cascade involved in growth hormone signaling pathway
mammary gland epithelial cell differentiation
prostate gland growth
mammary gland alveolus development

Function(s)

prolactin receptor activity
protein binding
peptide hormone binding
protein homodimerization activity
ornithine decarboxylase activator activity
metal ion binding