92943

• Gene Symbol: Ago2
• Gene Name: argonaute RISC catalytic subunit 2
• Gene Aliases: 1110029L17Rik, 2310051F07Rik, AI225898, AL022874, AW546247, ENSMUSG00000072493, Eif2c2, Gerp95, Gm10365, mKIAA4215
• Chromosome Location: Chr.15: 73101625 - 73184947 on Build GRCm38
• UniGene ID: Mm.23095
• Species: Mouse
• Species Specific ID (Flybase ID): -

siRNA Details

Gene Symbol: Ago2
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	NM_153178.4	NP_694818.3	19	3068
GenBank mRNA	AK220193.1	-	16	2433
	BC023279.1	-	11	1769
	BC024857.1	-	12	1913
	BC056639.1	-	9	1635
	BC064741.1	-	14	2185
	BC096465.1	-	19	2973

More Information

Additional Information:

This siRNA no longer meets our design criteria. We suggest you choose a different siRNA for this gene or contact Tech Support for more information.

Gene Ontology Categories:

Process(es)

transcription, DNA-templated
regulation of transcription, DNA-templated
mRNA cleavage
regulation of translation
multicellular organism development
post-embryonic development
RNA secondary structure unwinding
miRNA metabolic process
positive regulation of gene expression
cell differentiation
gene silencing by RNA
pre-miRNA processing
siRNA loading onto RISC involved in RNA interference
production of miRNAs involved in gene silencing by miRNA
miRNA mediated inhibition of translation
mRNA cleavage involved in gene silencing by miRNA
miRNA loading onto RISC involved in gene silencing by miRNA
positive regulation of transcription from RNA polymerase II promoter
negative regulation of translational initiation
positive regulation of nuclear-transcribed mRNA poly(A) tail shortening
RNA phosphodiester bond hydrolysis, endonucleolytic
mRNA cleavage involved in gene silencing by siRNA
positive regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay

Function(s)

RNA 7-methylguanosine cap binding
RNA polymerase II core binding
core promoter binding
nucleic acid binding
RNA binding
double-stranded RNA binding
single-stranded RNA binding
mRNA binding
nuclease activity
endonuclease activity
endoribonuclease activity
protein binding
hydrolase activity
siRNA binding
miRNA binding
poly(A) RNA binding
metal ion binding
endoribonuclease activity, cleaving siRNA-paired mRNA
pre-miRNA binding
endoribonuclease activity, cleaving miRNA-paired mRNA