HSS144048

• Gene Symbol: SOX4
• Gene Name: SRY-box 4
• Gene Aliases: EVI16
• Chromosome Location: Chr.6: 21593741 - 21598619 on Build GRCh38
• UniGene ID: Hs.643910
• Species: Human
• Species Specific ID (Flybase ID): -

siRNA Details

Gene Symbol: SOX4
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	NM_003107.2	NP_003098.1	1	1148
GenBank mRNA	BC072668.1	-	2	968	6584346
	X65661.1	-	1	147
	X70683.1	-	1	704

More Information

Other Species Targeted

This siRNA also targets the following transcripts in Rat: NM_001271205.
This siRNA also targets the following transcripts in Mouse: NM_009238, AK028989, BC060669, AK053840, AF009414, and others.

Gene Ontology Categories:

Process(es)

skeletal system development
neural tube formation
pro-B cell differentiation
mitral valve morphogenesis
cardiac ventricle formation
cardiac right ventricle morphogenesis
atrial septum primum morphogenesis
noradrenergic neuron differentiation
regulation of transcription, DNA-templated
transcription from RNA polymerase II promoter
DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest
heart development
positive regulation of cell proliferation
negative regulation of cell proliferation
glial cell proliferation
spinal cord development
spinal cord motor neuron differentiation
glial cell development
positive regulation of Wnt signaling pathway
T cell differentiation
endocrine pancreas development
negative regulation of protein ubiquitination
regulation of protein stability
positive regulation of insulin secretion
somatic stem cell population maintenance
ascending aorta morphogenesis
glucose homeostasis
DNA damage response, detection of DNA damage
positive regulation of apoptotic process
positive regulation of translation
positive regulation of transcription, DNA-templated
positive regulation of transcription from RNA polymerase II promoter
negative regulation of protein export from nucleus
sympathetic nervous system development
protein stabilization
canonical Wnt signaling pathway
limb bud formation
ventricular septum morphogenesis
negative regulation of cell death
neuroepithelial cell differentiation
kidney morphogenesis
cellular response to glucose stimulus
positive regulation of canonical Wnt signaling pathway
positive regulation of N-terminal peptidyl-lysine acetylation

Function(s)

transcription regulatory region sequence-specific DNA binding
core promoter sequence-specific DNA binding
nucleic acid binding transcription factor activity
transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding
RNA polymerase II transcription coactivator activity
transcription factor activity, sequence-specific DNA binding
protein binding
protein heterodimerization activity