HSS144759

• Gene Symbol: OGT
• Gene Name: O-linked N-acetylglucosamine (GlcNAc) transferase
• Gene Aliases: HINCUT-1, HRNT1, O-GLCNAC
• Chromosome Location: Chr.X: 71533062 - 71575897 on Build GRCh38
• UniGene ID: Hs.405410
• Species: Human
• Species Specific ID (Flybase ID): -

siRNA Details

Gene Symbol: OGT
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	NM_181672.2	NP_858058.1	22	3259
	NM_181673.2	NP_858059.1	22	3229
	XM_017029907.1	XP_016885396.1	20	2788
	XM_017029908.1	XP_016885397.1	20	6261
GenBank mRNA	AF147394.1	-	4	468
	AF223393.1	-	18	2896
	AK313530.1	-	18	3175
	AL050366.1	-	17	4486
	AL833085.2	-	22	3239
	BC014434.1	-	22	3160	4865031
	BC038180.1	-	22	3192	5017795
	BX537844.1	-	22	3217
	U77413.1	-	18	2908

More Information

Other Species Targeted

This siRNA also targets the following transcripts in Rat: NM_017107, XM_006257058, XM_006257056, XM_006257057, CK355423.
This siRNA also targets the following transcripts in Mouse: NM_139144, NM_001290535, BC038435, AF363030, BC057319, and others.

Gene Ontology Categories:

Process(es)

positive regulation of protein phosphorylation
glucosamine metabolic process
regulation of glycolytic process
protein O-linked glycosylation
apoptotic process
signal transduction
response to nutrient
negative regulation of peptidyl-threonine phosphorylation
positive regulation of granulocyte differentiation
forebrain development
negative regulation of protein ubiquitination
response to insulin
cellular response to insulin stimulus
circadian regulation of gene expression
negative regulation of peptidyl-serine phosphorylation
regulation of Rac protein signal transduction
positive regulation of catalytic activity
histone H4-K5 acetylation
histone H4-K8 acetylation
histone H4-K16 acetylation
positive regulation of cell size
positive regulation of proteolysis
positive regulation of transcription from RNA polymerase II promoter
regulation of insulin receptor signaling pathway
phosphatidylinositol-mediated signaling
intracellular distribution of mitochondria
positive regulation of histone H3-K4 methylation
negative regulation of cell death
positive regulation of histone H3-K27 methylation
protein homotrimerization
protein heterotrimerization
cellular response to lipopolysaccharide
cellular response to retinoic acid
cellular response to glucose stimulus
histone H3-K4 trimethylation
negative regulation of protein targeting to membrane
regulation of gluconeogenesis involved in cellular glucose homeostasis
cellular response to toxic substance
negative regulation of cellular response to hypoxia
positive regulation of protein localization to nucleus
positive regulation of reactive oxygen species biosynthetic process

Function(s)

protein binding
phosphatidylinositol-3,4,5-trisphosphate binding
enzyme activator activity
transcription factor binding
acetylglucosaminyltransferase activity
protein N-acetylglucosaminyltransferase activity
protein domain specific binding
peptide binding
histone acetyltransferase activity (H4-K5 specific)
histone acetyltransferase activity (H4-K8 specific)
histone acetyltransferase activity (H4-K16 specific)
monosaccharide binding
protein O-GlcNAc transferase activity