HSS176194

• Gene Symbol: DLG4
• Gene Name: discs large MAGUK scaffold protein 4
• Gene Aliases: PSD95, SAP-90, SAP90
• Chromosome Location: Chr.17: 7189890 - 7220050 on Build GRCh38
• UniGene ID: Hs.463928
• Species: Human
• Species Specific ID (Flybase ID): -

siRNA Details

Gene Symbol: DLG4
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	NM_001128827.2	NP_001122299.1	18, 19	2441
	NM_001321074.1	NP_001308003.1	20, 21	3289
	NM_001321075.1	NP_001308004.1	18, 19	2450
	NM_001321076.1	NP_001308005.1	17, 18	2095
	NM_001321077.1	NP_001308006.1	17, 18	2086
	NM_001365.4	NP_001356.1	20, 21	3298
	XM_005256491.1	XP_005256548.1	18, 19	2540
	XM_011523698.1	XP_011522000.1	20, 21	3186
	XM_011523699.2	XP_011522001.1	21, 22	2428
	XM_011523702.1	XP_011522004.1	17, 18	1965
	XM_017024288.1	XP_016879777.1	17, 18	2186
	XM_017024289.1	XP_016879778.1	17, 18	2177
	XM_017024290.1	XP_016879779.1	17, 18	2655
GenBank mRNA	AK293835.1	-	18, 19	2447
	AK297346.1	-	17, 18	2043
	AK299801.1	-	17, 18	2057
	AK308533.1	-	17, 18	2200
	AK316096.1	-	18, 19	2003
	BC040533.1	-	12, 13	1443
	BC136553.1	-	20, 21	2822	9020543
	U83192.1	-	20, 21	2956

More Information

Other Species Targeted

This siRNA also targets the following transcripts in Rat: NM_019621, XM_006246686, XM_006246689, XM_006246681, XM_006246687, and others.
This siRNA also targets the following transcripts in Mouse: NM_007864, NM_001109752, BC014807, AK028242, D50621.

Gene Ontology Categories:

Process(es)

MAPK cascade
negative regulation of receptor internalization
protein complex assembly
signal transduction
positive regulation of cytosolic calcium ion concentration
chemical synaptic transmission
nervous system development
learning
synaptic vesicle maturation
ion transmembrane transport
social behavior
protein localization to synapse
locomotory exploration behavior
positive regulation of GTPase activity
establishment of protein localization
establishment or maintenance of epithelial cell apical/basal polarity
GMP metabolic process
GDP metabolic process
regulation of long-term neuronal synaptic plasticity
positive regulation of synaptic transmission
neuromuscular process controlling balance
dendritic spine morphogenesis
vocalization behavior
AMPA glutamate receptor clustering
receptor localization to synapse
regulation of N-methyl-D-aspartate selective glutamate receptor activity
positive regulation of excitatory postsynaptic potential
regulation of grooming behavior

Function(s)

guanylate kinase activity
Ras guanyl-nucleotide exchange factor activity
protein binding
protein C-terminus binding
ligand-gated ion channel activity
kinase binding
protein phosphatase binding
PDZ domain binding
beta-1 adrenergic receptor binding
D1 dopamine receptor binding
P2Y1 nucleotide receptor binding
protein complex binding
acetylcholine receptor binding
ionotropic glutamate receptor binding
neuroligin family protein binding
scaffold protein binding